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Figure 3


Fig. 3. In vitro neurosphere migration assay. (A) SVZ neurospheres cultured on poly-L-ornithine and laminin-coated coverslips migrate outwards radially. Scale bar: 200 µm. (B) 48 hours after adhesion, AQP4 knockout significantly decreased the distance of radial migration of SVZ neurospheres compared with the Aqp4+/+ control (*P<0.05).