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Figure 5


Fig. 5. The effect of PUVA on eIF2{alpha} phosphorylation and cell-cycle progression. (A) Immunoblot of G1-synchronised wild-type cells exposed to psoralen and 0 or 10 kJ/m2 of UVA. (B) Flow cytometry histograms of G1-synchronised wild-type cells irradiated (unshaded) and not irradiated (shaded) and incubated for the times indicated (in minutes) after exposure. (C) Pre-RC assay of G1-synchronised cells at different time points after exposure to 0 (control) or 10 kJ/m2 of UVA.