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Figure 1


Fig. 1. Sequence analysis of the Tetrahymena IFT122A gene. (A) An un-rooted neighbor-joining tree of IFT122A and other IFT and OSEG proteins, which share similar domain organization. Ce, Caenorhabditis elegans; Dm, Drosophila melanogaster; Hs, Homo sapiens; Tt, Tetrahymena thermophila. The number at the branches indicates the value of 1000 bootstraps. (B) Primary and secondary structure analysis of Ift122Ap. Yellow boxes indicate six WD motifs, and green boxes show two degenerate TRP-like repeat units. Secondary structure prediction shows two distinct regions of Ift122Ap: an N-terminal β-strand-rich region (yellow) and an {alpha}-helix-rich region (green). (C) Sequence alignment of the degenerate repeat units on Ift122Ap. Identical residues are shaded.