Fig. 3. POPX2 inhibits RhoAV14-induced and active-mDia-induced SRF-mediated transcription. The different plasmid constructs were transfected into COS7 cells as described in the Materials and Methods section. (A) POPX2 inhibits RhoA-induced SRF activity. The transfections were as labelled. (B) POPX2 inhibits active-mDia-induced SRF activity. The transfections were as labelled. (C) POPX2 does not inhibit CDC42-induced SRF activity. The transfections were as labelled.