Fig. 1. LUMA orthologs and expression of LUMA mRNA in human tissues. (A) Some BLASTP search hits with murine LUMA as a template. (B) Organization of predicted domains in selected orthologous LUMA sequences. Black boxes represent TMDs. (C) Multiple-tissue panels of first-strand cDNAs were tested for LUMA and, as a control, for glyceraldehyde-3-phosphate dehydrogenase (G3PDH) expression by semi-quantitative reverse transcriptase (RT)-PCR.