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Figure 6


Fig. 6. Effect of lowering LRP1 levels upon internal PrPC in sensory neurons. (A-F) Neurons treated for 4 hours with 250 nM siRNACon (A,C,E) or siRNALRP1.1 (B,D,F) were fixed, permeabilised and immunolabelled for PrPC (green) and (in red) BiP (A,B), {alpha}-mannosidase II (C,D) or syntaxin 6 (E,F). Bars, 5 µm.