Fig. 5. siRNAs targeting GAS5 protect the long-term survival of CEM-C7 T-leukemic cells after serum withdrawal or dexamethasone treatment. CEM-C7 cells were treated with GAS5 siRNAs and cultured either without serum or in the presence of dexamethasone (1 µM) for 72 hours. Colony-forming ability was then determined by plating in soft agar. Data are the mean ± s.e.m. from six independent experiments. ^*P<0.01 compared with (–)siRNA.