Fig. 1. slk1 encodes a serine-threonine protein kinase similar to S. pombe Sid2. (A) Schematic representation of the Slk1 domains. The kinase domain is represented in black and the AGC-kinase C-terminal domain is represented in grey. The amino acid positions of these domains are indicated. (B) Sequence comparison of Slk1 and related proteins. Sequence alignment was generated using CLC Free Workbench 4.0.3 software (CLC Bio, Aarhus, Denmark). Shading was performed with the Boxshade 3.21 program at the http://www.ch.embnet.org/server. Identical amino acids are highlighted in black and similar amino acids are highlighted in grey. Sp, Schizosaccharomyces pombe; Sc, Saccharomyces cerevisiae; Hs, Homo sapiens. (C) The phylogenetic tree was constructed using CLC Free Workbench 4.0.3 software according to the UPGMA algorithm.