Fig. 2. Genomic structures of muscle-specific miRNAs and their sequence homologies. (A) The genomic locations of muscle-specific miRNA genes, including miR-1-1/miR-133a-2, miR-1-2/miR-133a-1, miR-206/miR-133b, miR-208a, miR-208b and miR-499, on mouse chromosomes. The expression of these miRNAs and the host genes in which they reside are also indicated. (B) Comparison of muscle-specific miRNA sequences (shown 5'-3'). Matching colors indicate the homology of miRNA gene families, whereas the black coloring marks nucleotide differences.