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Figure 2


Fig. 2. Ultrastructural localization of CPDs. Example of a human XP2OS-SV fibroblast, immunolabeled using a specific antibody against CPDs, that has been (A) mock treated and (B) fixed 10 minutes after global UV-C irradiation at 60 J.m–2. Samples were contrasted with the EDTA regressive technique in order to reduce the contrast of chromatin. Arrowheads indicate condensed chromatin; arrows designate the perichromatin region. Scale bars: 0.5 µm.