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Figure 4


Fig. 4. Increase in the amount of dense chromatin areas upon global UV-C irradiation. XP2OS-SV EGFP-XPA-expressing cells were (A,C) mock treated or (B,D) fixed 10 minutes after global UV irradiation at 60 J.m–2, and subsequently stained with osmium ammine to specifically visualize DNA (dark color). The analyzed sections were collected at the middle nuclear plane of the cells. C and D represent close-ups of the boxed areas in A and B, respectively. IC, interchromatin compartment. Scale bars: 1.25 µm.