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Journal of Cell Science, Vol 101, Issue 3 517-528, Copyright © 1992 by Company of Biologists
JOURNAL ARTICLES |
J Marks, C Fankhauser, A Reymond and V Simanis
Unite de Recherche sur le cycle cellulaire, ISREC, Epalinges, Switzerland.
The cdc10 gene of the fission yeast S. pombe is required for traverse of the start control in late G1 and commitment to the mitotic cell cycle. To increase our understanding of the events which occur at start, a pseudoreversion analysis was undertaken to identify genes whose products may interact with cdc10 or bypass the requirement for it. A single gene, sct1+ (suppressor of cdc ten), has been identified, mutation of which suppresses all conditional alleles and a null allele of cdc10. Bypass of the requirement for cdc10+ function by sct1-1 mutations leads to pleiotropic defects, including microtubule, microfilament and nuclear structural abnormalities. Our data suggest that sct1 encodes a protein that is dependent upon cdc10+ either for its normal function or expression, or is a component of a checkpoint that monitors execution of p85cdc10 function.
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S. Tournier and J. B.A. Millar A Role for the START Gene-specific Transcription Factor Complex in the Inactivation of Cyclin B and Cut2 Destruction Mol. Biol. Cell, October 1, 2000; 11(10): 3411 - 3424. [Abstract] [Full Text]
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S. Whitehall, P. Stacey, K. Dawson, and N. Jones Cell Cycle-regulated Transcription in Fission Yeast: Cdc10-Res Protein Interactions during the Cell Cycle and Domains Required for Regulated Transcription Mol. Biol. Cell, November 1, 1999; 10(11): 3705 - 3715. [Abstract] [Full Text]
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 W. H. McDonald, R. Ohi, N. Smelkova, D. Frendewey, and K. L. Gould Myb-Related Fission Yeast cdc5p Is a Component of a 40S snRNP-Containing Complex and Is Essential for Pre-mRNA Splicing Mol. Cell. Biol., August 1, 1999; 19(8): 5352 - 5362. [Abstract] [Full Text] [PDF]
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R. R. West, E. V. Vaisberg, R. Ding, P. Nurse, and J. R. McIntosh cut11+: A Gene Required for Cell Cycle-dependent Spindle Pole Body Anchoring in the Nuclear Envelope and Bipolar Spindle Formation in Schizosaccharomyces pombe Mol. Biol. Cell, October 1, 1998; 9(10): 2839 - 2855. [Abstract] [Full Text]
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 N. Rhind and P. Russell The Schizosaccharomyces pombe S-Phase Checkpoint Differentiates Between Different Types of DNA Damage Genetics, August 1, 1998; 149(4): 1729 - 1737. [Abstract] [Full Text] [PDF]
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