|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 104, Issue 2 485-493, Copyright © 1993 by Company of Biologists
JOURNAL ARTICLES |
M Sipiczki, B Grallert and I Miklos
Department of Genetics, University of Debrecen, Hungary.
Mutation in the gene sep1+ of the unicellular fission yeast Schizosaccharomyces pombe impairs cell separation after cytokinesis and confers a branching mycelial morphology. The mutant is not defective in cell wall beta-glucanase activity but shows increased sensitivity to Ca2+ and Mg2+, and increased resistance to the microtubule inhibitor benomyl. The mycelial growth of sep1-1 provides a convenient method for the examination of the polar growth pattern and for pedigree analysis as demonstrated by the segregation of mating types in the homothallic microhyphae. sep1 is closely linked to ade1 (0.94 cM) on the right arm of chromosome II. The ts mutation spl1-1 confers a bent cell shape and causes aberrant septum formation at the restrictive temperature. sep1+ and spl1+ perform closely related functions as their mutant alleles interact with each other and with another septation mutant cdc4-8. These functions may overlap with certain cytoskeletal processes and with the determination of cell polarity because the triple mutant forms huge multinucleate syncytia with promiscuous branching and rare septum formation.
This article has been cited by other articles:
|
|
 |
|
  T. Linder, N. N. Rasmussen, C. O. Samuelsen, E. Chatzidaki, V. Baraznenok, J. Beve, P. Henriksen, C. M. Gustafsson, and S. Holmberg Two conserved modules of Schizosaccharomyces pombe Mediator regulate distinct cellular pathways Nucleic Acids Res., May 1, 2008; 36(8): 2489 - 2504. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Morrell-Falvey, L. Ren, A. Feoktistova, G. D. Haese, and K. L. Gould Cell wall remodeling at the fission yeast cell division site requires the Rho-GEF Rgf3p J. Cell Sci., December 1, 2005; 118(23): 5563 - 5573. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Amoah-Buahin, N. Bone, and J. Armstrong Hyphal Growth in the Fission Yeast Schizosaccharomyces pombe Eukaryot. Cell, July 1, 2005; 4(7): 1287 - 1297. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. L. Alonso-Nunez, H. An, A. B. Martin-Cuadrado, S. Mehta, C. Petit, M. Sipiczki, F. del Rey, K. L. Gould, and C. R. Vazquez de Aldana Ace2p Controls the Expression of Genes Required for Cell Separation in Schizosaccharomyces pombe Mol. Biol. Cell, April 1, 2005; 16(4): 2003 - 2017. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Bulmer, A. Pic-Taylor, S. K. Whitehall, K. A. Martin, J. B. A. Millar, J. Quinn, and B. A. Morgan The Forkhead Transcription Factor Fkh2 Regulates the Cell Division Cycle of Schizosaccharomyces pombe Eukaryot. Cell, August 1, 2004; 3(4): 944 - 954. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Dekker, D. Speijer, C. H. Grun, M. van den Berg, A. de Haan, and F. Hochstenbach Role of the {alpha}-Glucanase Agn1p in Fission-Yeast Cell Separation Mol. Biol. Cell, August 1, 2004; 15(8): 3903 - 3914. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. BALUSKA, D. VOLKMANN, and P. W. BARLOW Eukaryotic Cells and their Cell Bodies: Cell Theory Revised Ann. Bot., July 1, 2004; 94(1): 9 - 32. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Q.-W. Jin and D. McCollum Scw1p Antagonizes the Septation Initiation Network To Regulate Septum Formation and Cell Separation in the Fission Yeast Schizosaccharomyces pombe Eukaryot. Cell, June 1, 2003; 2(3): 510 - 520. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. B. Martin-Cuadrado, E. Duenas, M. Sipiczki, C. R. V. de Aldana, and F. del Rey The endo-{beta}-1,3-glucanase eng1p is required for dissolution of the primary septum during cell separation in Schizosaccharomyces pombe J. Cell Sci., May 1, 2003; 116(9): 1689 - 1698. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Berlin, A. Paoletti, and F. Chang Mid2p stabilizes septin rings during cytokinesis in fission yeast J. Cell Biol., March 31, 2003; 160(7): 1083 - 1092. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Karagiannis, R. Oulton, and P. G. Young The Scw1 RNA-Binding Domain Protein Regulates Septation and Cell-Wall Structure in Fission Yeast Genetics, September 1, 2002; 162(1): 45 - 58. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. W. Hendrickson, J. Yao, S. Bhadury, A. H. Corbett, and H. C. Joshi Conditional Mutations in {gamma}-Tubulin Reveal Its Involvement in Chromosome Segregation and Cytokinesis Mol. Biol. Cell, August 1, 2001; 12(8): 2469 - 2481. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. Jiang and R. L. Hallberg Isolation and Characterization of par1+ and par2+: Two Schizosaccharomyces pombe Genes Encoding B' Subunits of Protein Phosphatase 2A Genetics, March 1, 2000; 154(3): 1025 - 1038. [Abstract] [Full Text]
|
|
|
|
|
|
J. Demeter and S. Sazer imp2, a New Component of the Actin Ring in the Fission Yeast Schizosaccharomyces pombe J. Cell Biol., October 19, 1998; 143(2): 415 - 427. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Grallert, B. Grallert, B. Ribar, and M. Sipiczki Coordination of Initiation of Nuclear Division and Initiation of Cell Division in Schizosaccharomyces pombe: Genetic Interactions of Mutations J. Bacteriol., February 15, 1998; 180(4): 892 - 900. [Abstract] [Full Text]
|
|
|
|
 |
|
 K. L. Gould and V. Simanis The control of septum formation in fission yeast Genes & Dev., November 15, 1997; 11(22): 2939 - 2951. [Full Text] [PDF]
|
|
|
|
|
|
C. Kitayama, A. Sugimoto, and M. Yamamoto Type II Myosin Heavy Chain Encoded by the myo2 Gene Composes the Contractile Ring during Cytokinesis in Schizosaccharomyces pombe J. Cell Biol., June 16, 1997; 137(6): 1309 - 1319. [Abstract] [Full Text] [PDF]
|
|
