|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 104, Issue 2 583-593, Copyright © 1993 by Company of Biologists
JOURNAL ARTICLES |
R Gomes, RE Karess, H Ohkura, DM Glover and CE Sunkel
Laboratorio de Genetica Molecular, Centro de Citologia Experimental da Universidade do Porto, Portugal.
We describe a new mitotic locus of Drosophila melanogaster required for the progression through mitosis in the syncytial embryo and in late larval development. The locus aar (abnormal anaphase resolution) maps to the cytological interval 85E7-F16 and was identified by two alleles. The aar1 allele causes pupal lethality. Larval neuroblasts show an elevated mitotic index with high chromosome condensation and stretched and lagging chromatids during anaphase. aar2 produces fully viable but sterile females. aar1/aar2 females lay eggs that develop mitotic figures with similar abnormalities to those observed in neuroblasts. Indirect immunofluorescence of these embryos indicates that the centrosome cycle appears normal, although some abnormal spindle microtubules can be seen during mitosis.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  K. D. Cygnar, X. Gao, D. Pan, and T. P. Neufeld The Phosphatase Subunit Tap42 Functions Independently of Target of Rapamycin to Regulate Cell Division and Survival in Drosophila Genetics, June 1, 2005; 170(2): 733 - 740. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Bajpai, K. Makhijani, P. R. Rao, and L. S. Shashidhara Drosophila Twins regulates Armadillo levels in response to Wg/Wnt signal Development, March 1, 2004; 131(5): 1007 - 1016. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. Kao, S. Tuck, D. Baillie, and M. V. Sundaram C. elegans SUR-6/PR55 cooperates with LET-92/protein phosphatase 2A and promotes Raf activity independently of inhibitory Akt phosphorylation sites Development, February 15, 2004; 131(4): 755 - 765. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Deak, M. Donaldson, and D. M. Glover Mutations in makos, a Drosophila gene encoding the Cdc27 subunit of the anaphase promoting complex, enhance centrosomal defects in polo and are suppressed by mutations in twins/aar, which encodes a regulatory subunit of PP2A J. Cell Sci., October 15, 2003; 116(20): 4147 - 4158. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 B.-D. Wang and T.-T. Kuo Induction of a Mitosis Delay and Cell Lysis by High-Level Secretion of Mouse {alpha}-Amylase from Saccharomyces cerevisiae Appl. Envir. Microbiol., August 1, 2001; 67(8): 3693 - 3701. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Abdelilah-Seyfried, Y.-M. Chan, C. Zeng, N. J. Justice, S. Younger-Shepherd, L. E. Sharp, S. Barbel, S. A. Meadows, L. Y. Jan, and Y. N. Jan A Gain-of-Function Screen for Genes That Affect the Development of the Drosophila Adult External Sensory Organ Genetics, June 1, 2000; 155(2): 733 - 752. [Abstract] [Full Text]
|
|
|
|
|
|
J. Schumacher, N Ashcroft, P. Donovan, and A Golden A highly conserved centrosomal kinase, AIR-1, is required for accurate cell cycle progression and segregation of developmental factors in Caenorhabditis elegans embryos Development, January 11, 1998; 125(22): 4391 - 4402. [Abstract] [PDF]
|
|
|
|
 |
|
 D. A. Starr, B. C. Williams, Z. Li, B. Etemad-Moghadam, R. K. Dawe, and M. L. Goldberg Conservation of the Centromere/Kinetochore Protein ZW10 J. Cell Biol., September 22, 1997; 138(6): 1289 - 1301. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Williams, A. Dernburg, J Puro, S Nokkala, and M. Goldberg The Drosophila kinesin-like protein KLP3A is required for proper behavior of male and female pronuclei at fertilization Development, January 6, 1997; 124(12): 2365 - 2376. [Abstract] [PDF]
|
|
|
|
|
|
G Callaini, R Dallai, and M. Riparbelli Wolbachia-induced delay of paternal chromatin condensation does not prevent maternal chromosomes from entering anaphase in incompatible crosses of Drosophila simulans J. Cell Sci., January 1, 1997; 110(2): 271 - 280. [Abstract] [PDF]
|
|
|
|
|
|
H. Snaith, C. Armstrong, Y Guo, K Kaiser, and P. Cohen Deficiency of protein phosphatase 2A uncouples the nuclear and centrosome cycles and prevents attachment of microtubules to the kinetochore in Drosophila microtubule star (mts) embryos J. Cell Sci., January 12, 1996; 109(13): 3001 - 3012. [Abstract] [PDF]
|
|
|
|
|
|
R. Mayer-Jaekel, H Ohkura, P Ferrigno, N Andjelkovic, K Shiomi, T Uemura, D. Glover, and B. Hemmings Drosophila mutants in the 55 kDa regulatory subunit of protein phosphatase 2A show strongly reduced ability to dephosphorylate substrates of p34cdc2 J. Cell Sci., January 9, 1994; 107(9): 2609 - 2616. [Abstract] [PDF]
|
|
|
|
|
|
K Shiomi, M Takeichi, Y Nishida, Y Nishi, and T Uemura Alternative cell fate choice induced by low-level expression of a regulator of protein phosphatase 2A in the Drosophila peripheral nervous system Development, January 6, 1994; 120(6): 1591 - 1599. [Abstract] [PDF]
|
|
|
|
|
|
B. Williams and M. Goldberg Determinants of Drosophila zw10 protein localization and function J. Cell Sci., January 4, 1994; 107(4): 785 - 798. [Abstract] [PDF]
|
|
