spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Hird, S.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Hird, S.

Journal of Cell Science, Vol 109, Issue 2 525-533, Copyright © 1996 by Company of Biologists

JOURNAL ARTICLES

Cortical actin movements during the first cell cycle of the Caenorhabditis elegans embryo

S Hird
MRC Laboratory of Molecular Biology, Cambridge, UK.

The first division of the Caenorhabditis elegans embryo is unequal, generating daughter cells with distinct fates. The differences between the cells are believed to result from the partitioning of cytoplasmic determinants during the first cell cycle. Actin microfilaments play a critical, but poorly defined, role in this event. In this paper, the actin cortex in live embryos is studied during cytoplasmic localisation by fluorescently labelling microfilaments in oocytes and then using in vivo fluorescence microscopy to observe their behaviour. This reveals that there is a concerted movement of cortical actin to the anterior of the embryo at the time cytoplasmic localisation takes place. Furthermore, it is demonstrated that endogenous foci of F-actin are asymmetrically distributed following this event; these structures have previously been seen in fixed cortices. A model for the participation of the actin cytoskeleton in cytoplasmic localisation is presented based on these results.


This article has been cited by other articles:


Home page
 Biophys. JHome page
B. R. Daniels, B. C. Masi, and D. Wirtz
Probing Single-Cell Micromechanics In Vivo: The Microrheology of C. elegans Developing Embryos
Biophys. J., June 15, 2006; 90(12): 4712 - 4719.
[Abstract] [Full Text] [PDF]

Home page
 Mol. Biol. CellHome page
H. A. Benink, C. A. Mandato, and W. M. Bement
Analysis of Cortical Flow Models In Vivo
Mol. Biol. Cell, August 1, 2000; 11(8): 2553 - 2563.
[Abstract] [Full Text]

Home page
 DevelopmentHome page
L Alessa and D. Kropf
F-actin marks the rhizoid pole in living Pelvetia compressa zygotes
Development, January 1, 1999; 126(1): 201 - 209.
[Abstract] [PDF]

Home page
 J. Cell Sci.Home page
H. Keating and J. White
Centrosome dynamics in early embryos of Caenorhabditis elegans
J. Cell Sci., January 10, 1998; 111(20): 3027 - 3033.
[Abstract] [PDF]

Home page
 DevelopmentHome page
B Goldstein and S. Hird
Specification of the anteroposterior axis in Caenorhabditis elegans
Development, January 5, 1996; 122(5): 1467 - 1474.
[Abstract] [PDF]


© The Company of Biologists Ltd 1996