|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 109, Issue 4 727-738, Copyright © 1996 by Company of Biologists
JOURNAL ARTICLES |
MH Bre, V Redeker, M Quibell, J Darmanaden-Delorme, C Bressac, J Cosson, P Huitorel, JM Schmitter, J Rossler, T Johnson, A Adoutte and N Levilliers
Laboratoire de Biologie Cellulaire 4, URA 1134 CNRS, Universite de Paris-Sud, Orsay, France.
Two monoclonal antibodies, AXO 49 and TAP 952, probed with carboxy-terminal peptides from Paramecium axonemal tubulin and with polyglycylated synthetic peptides, are found to recognize differently tubulin polyglycylation, the most recently identified posttranslational modification discovered in Paramecium axonemal tubulin. With these antibodies, we show that tubulin polyglycylation is widely distributed in organisms ranging from ciliated protozoa to mammals; it arose early in the course of evolution, but seems to be absent in primitive protozoa such as the Euglenozoa. Tubulin polyglycylation is the last posttranslational modification which takes place in the course of Drosophila spermatogenesis and its occurrence corresponds to the end of spermatozoan maturation. An involvement of polyglycylated tubulin in axoneme motility is suggested since AXO 49 and TAP 952 specifically inhibit the reactivated motility of sea urchin spermatozoa.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  E. Nohynkova, P. Tumova, and J. Kulda Cell Division of Giardia intestinalis: Flagellar Developmental Cycle Involves Transformation and Exchange of Flagella between Mastigonts of a Diplomonad Cell. Eukaryot. Cell, April 1, 2006; 5(4): 753 - 761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. E. Williams, C.-C. Tsao, J. Bowen, G. L. Hehman, R. J. Williams, and J. Frankel The Actin Gene ACT1 Is Required for Phagocytosis, Motility, and Cell Separation of Tetrahymena thermophila Eukaryot. Cell, March 1, 2006; 5(3): 555 - 567. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Lalle, A. M. Salzano, M. Crescenzi, and E. Pozio The Giardia duodenalis 14-3-3 Protein Is Post-translationally Modified by Phosphorylation and Polyglycylation of the C-terminal Tail J. Biol. Chem., February 24, 2006; 281(8): 5137 - 5148. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Vent, T. A. Wyatt, D. D. Smith, A. Banerjee, R. F. Luduena, J. H. Sisson, and R. Hallworth Direct involvement of the isotype-specific C-terminus of {beta} tubulin in ciliary beating J. Cell Sci., October 1, 2005; 118(19): 4333 - 4341. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Redeker, N. Levilliers, E. Vinolo, J. Rossier, D. Jaillard, D. Burnette, J. Gaertig, and M.-H. Bre Mutations of Tubulin Glycylation Sites Reveal Cross-talk between the C Termini of {alpha}- and {beta}-Tubulin and Affect the Ciliary Matrix in Tetrahymena J. Biol. Chem., January 7, 2005; 280(1): 596 - 606. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Thazhath, M. Jerka-Dziadosz, J. Duan, D. Wloga, M. A. Gorovsky, J. Frankel, and J. Gaertig Cell Context-specific Effects of the {beta}-Tubulin Glycylation Domain on Assembly and Size of Microtubular Organelles Mol. Biol. Cell, September 1, 2004; 15(9): 4136 - 4147. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 T. Noguchi and K. G. Miller A role for actin dynamics in individualization during spermatogenesis in Drosophila melanogaster Development, May 1, 2003; 130(9): 1805 - 1816. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 L. Xia, B. Hai, Y. Gao, D. Burnette, R. Thazhath, J. Duan, M.-H. Bre, N. Levilliers, M. A. Gorovsky, and J. Gaertig Polyglycylation of Tubulin Is Essential and Affects Cell Motility and Division in Tetrahymena thermophila J. Cell Biol., May 29, 2000; 149(5): 1097 - 1106. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. M. Brown, C. Marsala, R. Kosoy, and J. Gaertig Kinesin-II Is Preferentially Targeted to Assembling Cilia and Is Required for Ciliogenesis and Normal Cytokinesis in Tetrahymena Mol. Biol. Cell, October 1, 1999; 10(10): 3081 - 3096. [Abstract] [Full Text]
|
|
|
|
|
|
K Million, J Larcher, J Laoukili, D Bourguignon, F Marano, and F Tournier Polyglutamylation and polyglycylation of alpha- and beta-tubulins during in vitro ciliated cell differentiation of human respiratory epithelial cells J. Cell Sci., January 12, 1999; 112(23): 4357 - 4366. [Abstract] [PDF]
|
|
|
|
|
|
M.-H. Bré, V. Redeker, J. Vinh, J. Rossier, and N. Levilliers Tubulin Polyglycylation: Differential Posttranslational Modification of Dynamic Cytoplasmic and Stable Axonemal Microtubules in Paramecium Mol. Biol. Cell, September 1, 1998; 9(9): 2655 - 2665. [Abstract] [Full Text]
|
|
|
|
|
|
A Santel, N Blumer, M Kampfer, and R Renkawitz-Pohl Flagellar mitochondrial association of the male-specific Don Juan protein in Drosophila spermatozoa J. Cell Sci., January 11, 1998; 111(22): 3299 - 3309. [Abstract] [PDF]
|
|
|
|
|
|
A Schneider, U Plessmann, and K Weber Subpellicular and flagellar microtubules of Trypanosoma brucei are extensively glutamylated J. Cell Sci., January 2, 1997; 110(4): 431 - 437. [Abstract] [PDF]
|
|
