|
|
|
||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 109, Issue 8 1991-2000, Copyright © 1996 by Company of Biologists
JOURNAL ARTICLES |
J Strouboulis and AP Wolffe
Laboratory of Molecular Embryology, National Institute of Child Health and Human Development, NIH, Bethesda, MD 20892-2710, USA.
Recent applications of cell biology and molecular genetics have built an image of nuclear organization in which the molecular machines involved in transcription, RNA processing and replication assemble morphologically distinct nuclear organelles with defined functional properties. These observations indicate a very high level of structural organization for the various metabolic activities occurring within the nucleus. We discuss the possible existence of novel regulatory functions inherent to nuclear architecture itself.
This article has been cited by other articles:
![]() |
K. A. Fryrear, S. S. Durkin, S. K. Gupta, J. B. Tiedebohl, and O. J. Semmes Dimerization and a Novel Tax Speckled Structure Localization Signal Are Required for Tax Nuclear Localization J. Virol., June 1, 2009; 83(11): 5339 - 5352. [Abstract] [Full Text] [PDF] |
||||
![]() |
T. Lechertier, V. Sirri, D. Hernandez-Verdun, and P. Roussel A B23-interacting sequence as a tool to visualize protein interactions in a cellular context J. Cell Sci., January 15, 2007; 120(2): 265 - 275. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. L. Arnett-Mansfield, J. D. Graham, A. R. Hanson, P. A. Mote, A. Gompel, L. L. Scurr, N. Gava, A. de Fazio, and C. L. Clarke Focal Subnuclear Distribution of Progesterone Receptor Is Ligand Dependent and Associated with Transcriptional Activity Mol. Endocrinol., January 1, 2007; 21(1): 14 - 29. [Abstract] [Full Text] [PDF] |
||||
![]() |
E. Louvet, H. R. Junera, I. Berthuy, and D. Hernandez-Verdun Compartmentation of the Nucleolar Processing Proteins in the Granular Component Is a CK2-driven Process Mol. Biol. Cell, June 1, 2006; 17(6): 2537 - 2546. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. Shahin, Y. Ludwig, C. Schafer, D. Nikova, and H. Oberleithner Glucocorticoids remodel nuclear envelope structure and permeability J. Cell Sci., July 1, 2005; 118(13): 2881 - 2889. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. L. Arnett-Mansfield, A. deFazio, P. A. Mote, and C. L. Clarke Subnuclear Distribution of Progesterone Receptors A and B in Normal and Malignant Endometrium J. Clin. Endocrinol. Metab., March 1, 2004; 89(3): 1429 - 1442. [Abstract] [Full Text] [PDF] |
||||
![]() |
H. Iida, A. Urasoko, M. Doiguchi, T. Mori, K. Toshimori, and Y. Shibata Complementary DNA Cloning and Characterization of Rat spergen-2, a Spermatogenic Cell-Specific Gene 2 Encoding a 56-Kilodalton Nuclear Protein Bearing Ankyrin Repeat Motifs Biol Reprod, August 1, 2003; 69(2): 421 - 429. [Abstract] [Full Text] [PDF] |
||||
![]() |
R. F. Irvine Nuclear Lipid Signaling Sci. Signal., September 17, 2002; 2002(150): re13 - re13. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Rodgers, S. J. Jordan, and J. D. Capra Transient Association of Ku with Nuclear Substrates Characterized Using Fluorescence Photobleaching J. Immunol., March 1, 2002; 168(5): 2348 - 2355. [Abstract] [Full Text] [PDF] |
||||
![]() |
F. Cammas, M. Oulad-Abdelghani, J.-L. Vonesch, Y. Huss-Garcia, P. Chambon, and R. Losson Cell differentiation induces TIF1{beta} association with centromeric heterochromatin via an HP1 interaction J. Cell Sci., January 9, 2002; 115(17): 3439 - 3448. [Abstract] [Full Text] [PDF] |
||||
![]() |
D. Hernandez-Verdun, P. Roussel, and J. Gebrane-Younes Emerging concepts of nucleolar assembly J. Cell Sci., January 6, 2002; 115(11): 2265 - 2270. [Abstract] [Full Text] [PDF] |
||||
![]() |
B. K. Kennedy, D. A. Barbie, M. Classon, N. Dyson, and E. Harlow Nuclear organization of DNA replication in primary mammalian cells Genes & Dev., November 15, 2000; 14(22): 2855 - 2868. [Abstract] [Full Text] |
||||
![]() |
D. A. Hume Probability in transcriptional regulation and its implications for leukocyte differentiation and inducible gene expression Blood, October 1, 2000; 96(7): 2323 - 2328. [Abstract] [Full Text] [PDF] |
||||
![]() |
O. Nayler, A. M. Hartmann, and S. Stamm The ER Repeat Protein YT521-B Localizes to a Novel Subnuclear Compartment J. Cell Biol., September 5, 2000; 150(5): 949 - 962. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. N. Szentirmay and M. Sawadogo SURVEY AND SUMMARY: Spatial organization of RNA polymerase II transcription in the nucleus Nucleic Acids Res., May 15, 2000; 28(10): 2019 - 2025. [Abstract] [Full Text] [PDF] |
||||
![]() |
W. Stünkel, Z. Huang, S.-H. Tan, M. J. O'Connor, and H.-U. Bernard Nuclear Matrix Attachment Regions of Human Papillomavirus Type 16 Repress or Activate the E6 Promoter, Depending on the Physical State of the Viral DNA J. Virol., March 15, 2000; 74(6): 2489 - 2501. [Abstract] [Full Text] |
||||
![]() |
D. A. JACKSON, A. POMBO, and F. IBORRA The balance sheet for transcription: an analysis of nuclear RNA metabolism in mammalian cells FASEB J, February 1, 2000; 14(2): 242 - 254. [Abstract] [Full Text] |
||||
![]() |
M Nogami, A Kohda, H Taguchi, M Nakao, T Ikemura, and K Okumura Relative locations of the centromere and imprinted SNRPN gene within chromosome 15 territories during the cell cycle in HL60 cells J. Cell Sci., January 6, 2000; 113(12): 2157 - 2165. [Abstract] [PDF] |
||||
![]() |
E. Volpi, E Chevret, T Jones, R Vatcheva, J Williamson, S Beck, R. Campbell, M Goldsworthy, S. Powis, J Ragoussis, et al. Large-scale chromatin organization of the major histocompatibility complex and other regions of human chromosome 6 and its response to interferon in interphase nuclei J. Cell Sci., January 5, 2000; 113(9): 1565 - 1576. [Abstract] [PDF] |
||||
![]() |
A. Taddei, D. Roche, J.-B. Sibarita, B. M. Turner, and G. Almouzni Duplication and Maintenance of Heterochromatin Domains J. Cell Biol., December 13, 1999; 147(6): 1153 - 1166. [Abstract] [Full Text] [PDF] |
||||
![]() |
N. Sadoni, S. Langer, C. Fauth, G. Bernardi, T. Cremer, B. M. Turner, and D. Zink Nuclear Organization of Mammalian Genomes: Polar Chromosome Territories Build Up Functionally Distinct Higher Order Compartments J. Cell Biol., September 20, 1999; 146(6): 1211 - 1226. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. G. Stacey and A. G. von Arnim A Novel Motif Mediates the Targeting of the Arabidopsis COP1 Protein to Subnuclear Foci J. Biol. Chem., September 17, 1999; 274(38): 27231 - 27236. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Yi, P. Wu, K. W. Trevorrow, L. Claflin, and W. T. Garrard Evidence That the Ig{kappa} Gene MAR Regulates the Probability of Premature V-J Joining and Somatic Hypermutation J. Immunol., May 15, 1999; 162(10): 6029 - 6039. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Panse, C Masson, L Heliot, J. Chassery, H. Junera, and D Hernandez-Verdun 3-D organization of ribosomal transcription units after DRB inhibition of RNA polymerase II transcription J. Cell Sci., January 7, 1999; 112(13): 2145 - 2154. [Abstract] [PDF] |
||||
![]() |
J. Ostashevsky A Polymer Model for the Structural Organization of Chromatin Loops and Minibands in Interphase Chromosomes Mol. Biol. Cell, November 1, 1998; 9(11): 3031 - 3040. [Abstract] [Full Text] |
||||
![]() |
C. Klein, T. Cheutin, M.-F. O'Donohue, L. Rothblum, H. Kaplan, A. Beorchia, L. Lucas, L. Héliot, and D. Ploton The Three-dimensional Study of Chromosomes and Upstream Binding Factor-immunolabeled Nucleolar Organizer Regions Demonstrates Their Nonrandom Spatial Arrangement during Mitosis Mol. Biol. Cell, November 1, 1998; 9(11): 3147 - 3159. [Abstract] [Full Text] |
||||
![]() |
R. Abranches, A. F. Beven, L. Aragon-Alcaide, and P. J. Shaw Transcription Sites Are Not Correlated with Chromosome Territories in Wheat Nuclei J. Cell Biol., October 5, 1998; 143(1): 5 - 12. [Abstract] [Full Text] [PDF] |
||||
![]() |
S. Gabler, H. Schutt, P. Groitl, H. Wolf, T. Shenk, and T. Dobner E1B 55-Kilodalton-Associated Protein: a Cellular Protein with RNA-Binding Activity Implicated in Nucleocytoplasmic Transport of Adenovirus and Cellular mRNAs J. Virol., October 1, 1998; 72(10): 7960 - 7971. [Abstract] [Full Text] [PDF] |
||||
![]() |
C. Verheggen, S. Le Panse, G. Almouzni, and D. Hernandez-Verdun Presence of Pre-rRNAs before Activation of Polymerase I Transcription in the Building Process of Nucleoli during Early Development of Xenopus laevis J. Cell Biol., September 7, 1998; 142(5): 1167 - 1180. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. J. Hendzel, M. J. Kruhlak, and D. P. Bazett-Jones Organization of Highly Acetylated Chromatin around Sites of Heterogeneous Nuclear RNA Accumulation Mol. Biol. Cell, September 1, 1998; 9(9): 2491 - 2507. [Abstract] [Full Text] |
||||
![]() |
C. Isaac, Y. Yang, and U. Thomas Meier Nopp140 Functions as a Molecular Link Between the Nucleolus and the Coiled Bodies J. Cell Biol., July 27, 1998; 142(2): 319 - 329. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Buchenau, J. Hodgson, H. Strutt, and D. J. Arndt-Jovin The Distribution of Polycomb-Group Proteins During Cell Division and Development in Drosophila Embryos: Impact on Models for Silencing J. Cell Biol., April 20, 1998; 141(2): 469 - 481. [Abstract] [Full Text] [PDF] |
||||
![]() |
N Itoh and N Shimizu DNA replication-dependent intranuclear relocation of double minute chromatin J. Cell Sci., January 11, 1998; 111(22): 3275 - 3285. [Abstract] [PDF] |
||||
![]() |
K Stankunas, J Berger, C Ruse, D. Sinclair, F Randazzo, and H. Brock The enhancer of polycomb gene of Drosophila encodes a chromatin protein conserved in yeast and mammals Development, January 10, 1998; 125(20): 4055 - 4066. [Abstract] [PDF] |
||||
![]() |
M Meyer-Ficca, J Muller-Navia, and H Scherthan Clustering of pericentromeres initiates in step 9 of spermiogenesis of the rat (Rattus norvegicus) and contributes to a well defined genome architecture in the sperm nucleus J. Cell Sci., January 5, 1998; 111(10): 1363 - 1370. [Abstract] [PDF] |
||||
![]() |
D. Sinclair, T. Milne, J. Hodgson, J Shellard, C. Salinas, M Kyba, F Randazzo, and H. Brock The Additional sex combs gene of Drosophila encodes a chromatin protein that binds to shared and unique Polycomb group sites on polytene chromosomes Development, January 4, 1998; 125(7): 1207 - 1216. [Abstract] [PDF] |
||||
![]() |
T. Sternsdorf, K. Jensen, D. Zuchner, and H. Will Cellular Localization, Expression, and Structure of the Nuclear Dot Protein 52 J. Cell Biol., July 28, 1997; 138(2): 435 - 448. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Liang, R. Amons, J. S. Clegg, and T. H. MacRae Molecular Characterization of a Small Heat Shock/alpha -Crystallin Protein in Encysted Artemia Embryos J. Biol. Chem., July 25, 1997; 272(30): 19051 - 19058. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Widlak, R. B. Gaynor, and W. T. Garrard In Vitro Chromatin Assembly of the HIV-1 Promoter. ATP-DEPENDENT POLAR REPOSITIONING OF NUCLEOSOMES BY Sp1 AND NFkappa B J. Biol. Chem., July 11, 1997; 272(28): 17654 - 17661. [Abstract] [Full Text] [PDF] |
||||
![]() |
J. C. Reyes, C. Muchardt, and M. Yaniv Components of the Human SWI/SNF Complex Are Enriched in Active Chromatin and Are Associated with the Nuclear Matrix J. Cell Biol., April 21, 1997; 137(2): 263 - 274. [Abstract] [Full Text] [PDF] |
||||
![]() |
P. Buchenau, H. Saumweber, and D. J. Arndt-Jovin The Dynamic Nuclear Redistribution of an hnRNP K-homologous Protein during Drosophila Embryo Development and Heat Shock. Flexibility of Transcription Sites In Vivo J. Cell Biol., April 21, 1997; 137(2): 291 - 303. [Abstract] [Full Text] [PDF] |
||||
![]() |
V. C. Cordes, S. Reidenbach, H.-R. Rackwitz, and W. W. Franke Identification of Protein p270/Tpr as a Constitutive Component of the Nuclear Pore Complex-attached Intranuclear Filaments J. Cell Biol., February 10, 1997; 136(3): 515 - 529. [Abstract] [Full Text] [PDF] |
||||
![]() |
M. Fricker, M. Hollinshead, N. White, and D. Vaux Interphase Nuclei of Many Mammalian Cell Types Contain Deep, Dynamic, Tubular Membrane-bound Invaginations of the Nuclear Envelope J. Cell Biol., February 10, 1997; 136(3): 531 - 544. [Abstract] [Full Text] [PDF] |
||||
![]() |
C Jolly, R Morimoto, M Robert-Nicoud, and C Vourc'h HSF1 transcription factor concentrates in nuclear foci during heat shock: relationship with transcription sites J. Cell Sci., January 12, 1997; 110(23): 2935 - 2941. [Abstract] [PDF] |
||||
![]() |
G Zimowska, J. Aris, and M. Paddy A Drosophila Tpr protein homolog is localized both in the extrachromosomal channel network and to nuclear pore complexes J. Cell Sci., January 4, 1997; 110(8): 927 - 944. [Abstract] [PDF] |
||||