|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 111, Issue 1 1-9, Copyright © 1998 by Company of Biologists
JOURNAL ARTICLES |
RE Brown
The Hormel Institute, University of Minnesota, Austin, MN 55912, USA.
Recent cell biological studies suggest that sphingolipids and cholesterol may cluster in biomembranes to form raft-like microdomains. Such lipid domains are postulated to function as platforms involved in the lateral sorting of certain proteins during their trafficking within cells as well as during signal transduction events. Here, the physical interactions that occur between cholesterol and sphingolipids in model membrane systems are discussed within the context of microdomain formation. A model is presented in which the role of cholesterol is refined compared to earlier models.
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  I. Bottova, A. B. Hehl, S. Stefanic, G. Fabrias, J. Casas, E. Schraner, J. Pieters, and S. Sonda Host Cell P-glycoprotein Is Essential for Cholesterol Uptake and Replication of Toxoplasma gondii J. Biol. Chem., June 26, 2009; 284(26): 17438 - 17448. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 E. Bonzon-Kulichenko, D. Schwudke, N. Gallardo, E. Molto, T. Fernandez-Agullo, A. Shevchenko, and A. Andres Central Leptin Regulates Total Ceramide Content and Sterol Regulatory Element Binding Protein-1C Proteolytic Maturation in Rat White Adipose Tissue Endocrinology, January 1, 2009; 150(1): 169 - 178. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Lingwood, J. Ries, P. Schwille, and K. Simons Plasma membranes are poised for activation of raft phase coalescence at physiological temperature PNAS, July 22, 2008; 105(29): 10005 - 10010. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. A. Sanchez, M. A. Tricerri, and E. Gratton Interaction of high density lipoprotein particles with membranes containing cholesterol J. Lipid Res., August 1, 2007; 48(8): 1689 - 1700. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. Delmas, M. Breton, C. Sapin, A. Le Bivic, O. Colard, and G. Trugnan Heterogeneity of Raft-Type Membrane Microdomains Associated with VP4, the Rotavirus Spike Protein, in Caco-2 and MA 104 Cells J. Virol., February 15, 2007; 81(4): 1610 - 1618. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Laloi, A.-M. Perret, L. Chatre, S. Melser, C. Cantrel, M.-N. Vaultier, A. Zachowski, K. Bathany, J.-M. Schmitter, M. Vallet, et al. Insights into the Role of Specific Lipids in the Formation and Delivery of Lipid Microdomains to the Plasma Membrane of Plant Cells Plant Physiology, January 1, 2007; 143(1): 461 - 472. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Q. Huang, H.-M. Shen, G. Shui, M. R. Wenk, and C.-N. Ong Emodin Inhibits Tumor Cell Adhesion through Disruption of the Membrane Lipid Raft-Associated Integrin Signaling Pathway Cancer Res., June 1, 2006; 66(11): 5807 - 5815. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Sugama, S. Ohkubo, M. Atsumi, and N. Nakahata Mastoparan Changes the Cellular Localization of G{alpha}q/11 and G{beta} through Its Binding to Ganglioside in Lipid Rafts Mol. Pharmacol., November 1, 2005; 68(5): 1466 - 1474. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. Yoshino, S. R. G. Setty, C. Poynton, E. L. Whiteman, A. Saint-Pol, C. G. Burd, L. Johannes, E. L. Holzbaur, M. Koval, J. M. McCaffery, et al. tGolgin-1 (p230, golgin-245) modulates Shiga-toxin transport to the Golgi and Golgi motility towards the microtubule-organizing centre J. Cell Sci., May 15, 2005; 118(10): 2279 - 2293. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
V. Gouaze, Y.-Y. Liu, C. S. Prickett, J. Y. Yu, A. E. Giuliano, and M. C. Cabot Glucosylceramide Synthase Blockade Down-Regulates P-Glycoprotein and Resensitizes Multidrug-Resistant Breast Cancer Cells to Anticancer Drugs Cancer Res., May 1, 2005; 65(9): 3861 - 3867. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. Ishitsuka, S. B. Sato, and T. Kobayashi Imaging Lipid Rafts J. Biochem., March 1, 2005; 137(3): 249 - 254. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Modok, C. Heyward, and R. Callaghan P-glycoprotein retains function when reconstituted into a sphingolipid- and cholesterol-rich environment J. Lipid Res., October 1, 2004; 45(10): 1910 - 1918. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Cabrera-Poch, L. Sanchez-Ruiloba, M. Rodriguez-Martinez, and T. Iglesias Lipid Raft Disruption Triggers Protein Kinase C and Src-dependent Protein Kinase D Activation and Kidins220 Phosphorylation in Neuronal Cells J. Biol. Chem., July 2, 2004; 279(27): 28592 - 28602. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Brugger, C. Graham, I. Leibrecht, E. Mombelli, A. Jen, F. Wieland, and R. Morris The Membrane Domains Occupied by Glycosylphosphatidylinositol-anchored Prion Protein and Thy-1 Differ in Lipid Composition J. Biol. Chem., February 27, 2004; 279(9): 7530 - 7536. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. J. Westover, D. F. Covey, H. L. Brockman, R. E. Brown, and L. J. Pike Cholesterol Depletion Results in Site-specific Increases in Epidermal Growth Factor Receptor Phosphorylation due to Membrane Level Effects: STUDIES WITH CHOLESTEROL ENANTIOMERS J. Biol. Chem., December 19, 2003; 278(51): 51125 - 51133. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Nichols Caveosomes and endocytosis of lipid rafts J. Cell Sci., December 1, 2003; 116(23): 4707 - 4714. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. A. Scheidt, P. Muller, A. Herrmann, and D. Huster The Potential of Fluorescent and Spin-labeled Steroid Analogs to Mimic Natural Cholesterol J. Biol. Chem., November 14, 2003; 278(46): 45563 - 45569. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B. Pei and J.-W. Chen More Ordered, Convex Ganglioside-Enriched Membrane Domains: The Effects of GM1 on Sphingomyelin Bilayers Containing a Low Level of Cholesterol J. Biochem., October 1, 2003; 134(4): 575 - 581. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. V. Subbaiah, S. J. Billington, B. H. Jost, J. G. Songer, and Y. Lange Sphingomyelinase D, a novel probe for cellular sphingomyelin: effects on cholesterol homeostasis in human skin fibroblasts J. Lipid Res., August 1, 2003; 44(8): 1574 - 1580. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
N. Kahya, D. Scherfeld, K. Bacia, B. Poolman, and P. Schwille Probing Lipid Mobility of Raft-exhibiting Model Membranes by Fluorescence Correlation Spectroscopy J. Biol. Chem., July 18, 2003; 278(30): 28109 - 28115. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. L. TUMA and A. L. HUBBARD Transcytosis: Crossing Cellular Barriers Physiol Rev, July 1, 2003; 83(3): 871 - 932. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Hoekstra, O. Maier, J. M. van der Wouden, T. A. Slimane, and S. C. D. van IJzendoorn Membrane dynamics and cell polarity: the role of sphingolipids J. Lipid Res., May 1, 2003; 44(5): 869 - 877. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. G. Briggs, T. Wilk, and S. D. Fuller Do lipid rafts mediate virus assembly and pseudotyping? J. Gen. Virol., April 1, 2003; 84(4): 757 - 768. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Rujoi, J. Jin, D. Borchman, D. Tang, and M. C. Yappert Isolation and Lipid Characterization of Cholesterol-Enriched Fractions in Cortical and Nuclear Human Lens Fibers Invest. Ophthalmol. Vis. Sci., April 1, 2003; 44(4): 1634 - 1642. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. C. Morrow, S. Rea, S. Martin, I. A. Prior, R. Prohaska, J. F. Hancock, D. E. James, and R. G. Parton Flotillin-1/Reggie-2 Traffics to Surface Raft Domains via a Novel Golgi-independent Pathway. IDENTIFICATION OF A NOVEL MEMBRANE TARGETING DOMAIN AND A ROLE FOR PALMITOYLATION J. Biol. Chem., December 6, 2002; 277(50): 48834 - 48841. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
B.-L. Waarts, R. Bittman, and J. Wilschut Sphingolipid and Cholesterol Dependence of Alphavirus Membrane Fusion. LACK OF CORRELATION WITH LIPID RAFT FORMATION IN TARGET LIPOSOMES J. Biol. Chem., October 4, 2002; 277(41): 38141 - 38147. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Mahfoud, M. Mylvaganam, C. A. Lingwood, and J. Fantini A novel soluble analog of the HIV-1 fusion cofactor, globotriaosylceramide (Gb3), eliminates the cholesterol requirement for high affinity gp120/Gb3 interaction J. Lipid Res., October 1, 2002; 43(10): 1670 - 1679. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. G. W. Anderson and K. Jacobson A Role for Lipid Shells in Targeting Proteins to Caveolae, Rafts, and Other Lipid Domains Science, June 7, 2002; 296(5574): 1821 - 1825. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Mattjus, B. Malewicz, J. T. Valiyaveettil, W. J. Baumann, R. Bittman, and R. E. Brown Sphingomyelin Modulates the Transbilayer Distribution of Galactosylceramide in Phospholipid Membranes J. Biol. Chem., May 24, 2002; 277(22): 19476 - 19481. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Mahfoud, N. Garmy, M. Maresca, N. Yahi, A. Puigserver, and J. Fantini Identification of a Common Sphingolipid-binding Domain in Alzheimer, Prion, and HIV-1 Proteins J. Biol. Chem., March 22, 2002; 277(13): 11292 - 11296. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. A. Alonso and J. Millan The role of lipid rafts in signalling and membrane trafficking in T lymphocytes J. Cell Sci., March 13, 2002; 114(22): 3957 - 3965. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. S. Worgall, R. A. Johnson, T. Seo, H. Gierens, and R. J. Deckelbaum Unsaturated Fatty Acid-mediated Decreases in Sterol Regulatory Element-mediated Gene Transcription Are Linked to Cellular Sphingolipid Metabolism J. Biol. Chem., February 1, 2002; 277(6): 3878 - 3885. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hao, S. Mukherjee, and F. R. Maxfield Cholesterol depletion induces large scale domain segregation in living cell membranes PNAS, November 6, 2001; 98(23): 13072 - 13077. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Seveau, R. J. Eddy, F. R. Maxfield, and L. M. Pierini Cytoskeleton-dependent Membrane Domain Segregation during Neutrophil Polarization Mol. Biol. Cell, November 1, 2001; 12(11): 3550 - 3562. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. C. M. Holthuis, T. Pomorski, R. J. Raggers, H. Sprong, and G. Van Meer The Organizing Potential of Sphingolipids in Intracellular Membrane Transport Physiol Rev, October 1, 2001; 81(4): 1689 - 1723. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Simons, E.-M. Kramer, C. Thiele, W. Stoffel, and J. Trotter Assembly of Myelin by Association of Proteolipid Protein with Cholesterol- and Galactosylceramide-Rich Membrane Domains J. Cell Biol., October 2, 2000; 151(1): 143 - 154. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 N. J. Boerth, J. J. Sadler, D. E. Bauer, J. L. Clements, S. M. Gheith, and G. A. Koretzky Recruitment of Slp-76 to the Membrane and Glycolipid-Enriched Membrane Microdomains Replaces the Requirement for Linker for Activation of T Cells in T Cell Receptor Signaling J. Exp. Med., October 2, 2000; 192(7): 1047 - 1058. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Klapisz, J. Masliah, G. Béréziat, C. Wolf, and K. S. Koumanov Sphingolipids and cholesterol modulate membrane susceptibility to cytosolic phospholipase A2 J. Lipid Res., October 1, 2000; 41(10): 1680 - 1688. [Abstract] [Full Text]
|
|
|
|
|
|
E. B. Babiychuk and A. Draeger Annexins in Cell Membrane Dynamics: Ca2+-Regulated Association of Lipid Microdomains J. Cell Biol., September 4, 2000; 150(5): 1113 - 1124. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. P. Levine, C. A.R. Wiggins, and S. Munro Inositol Phosphorylceramide Synthase Is Located in the Golgi Apparatus of Saccharomyces cerevisiae Mol. Biol. Cell, July 1, 2000; 11(7): 2267 - 2281. [Abstract] [Full Text]
|
|
|
|
|
|
X. Lin, P. Mattjus, H. M. Pike, A. J. Windebank, and R. E. Brown Cloning and Expression of Glycolipid Transfer Protein from Bovine and Porcine Brain J. Biol. Chem., February 18, 2000; 275(7): 5104 - 5110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Moffett, D. A. Brown, and M. E. Linder Lipid-dependent Targeting of G Proteins into Rafts J. Biol. Chem., January 21, 2000; 275(3): 2191 - 2198. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S Lecat, P Verkade, C Thiele, K Fiedler, K Simons, and F Lafont Different properties of two isoforms of annexin XIII in MDCK cells J. Cell Sci., January 7, 2000; 113(14): 2607 - 2618. [Abstract] [PDF]
|
|
|
|
|
|
P. V. Subbaiah, V. S. Subramanian, and K. Wang Novel Physiological Function of Sphingomyelin in Plasma. INHIBITION OF LIPID PEROXIDATION IN LOW DENSITY LIPOPROTEINS J. Biol. Chem., December 17, 1999; 274(51): 36409 - 36414. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. L. Munn, A. Heese-Peck, B. J. Stevenson, H. Pichler, and H. Riezman Specific Sterols Required for the Internalization Step of Endocytosis in Yeast Mol. Biol. Cell, November 1, 1999; 10(11): 3943 - 3957. [Abstract] [Full Text]
|
|
|
|
|
|
E.-M. Kramer, C. Klein, T. Koch, M. Boytinck, and J. Trotter Compartmentation of Fyn Kinase with Glycosylphosphatidylinositol-anchored Molecules in Oligodendrocytes Facilitates Kinase Activation during Myelination J. Biol. Chem., October 8, 1999; 274(41): 29042 - 29049. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H.L. Zhang, R.H. Singer, and G.J. Bassell Neurotrophin Regulation of {beta}-Actin mRNA and Protein Localization within Growth Cones J. Cell Biol., October 4, 1999; 147(1): 59 - 70. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Abrami and F. G. van der Goot Plasma Membrane Microdomains Act as Concentration Platforms to Facilitate Intoxication by Aerolysin J. Cell Biol., October 4, 1999; 147(1): 175 - 184. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Oliferenko, K. Paiha, T. Harder, V. Gerke, C. Schwarzler, H. Schwarz, H. Beug, U. Gunthert, and L. A. Huber Analysis of Cd44-Containing Lipid Rafts: Recruitment of Annexin II and Stabilization by the Actin Cytoskeleton J. Cell Biol., August 23, 1999; 146(4): 843 - 854. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Subtil, I. Gaidarov, K. Kobylarz, M. A. Lampson, J. H. Keen, and T. E. McGraw Acute cholesterol depletion inhibits clathrin-coated pit budding PNAS, June 8, 1999; 96(12): 6775 - 6780. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 W. Zhang, B. J. Irvin, R. P. Trible, R. T. Abraham, and L. E. Samelson Functional analysis of LAT in TCR-mediated signaling pathways using a LAT-deficient Jurkat cell line Int. Immunol., June 1, 1999; 11(6): 943 - 950. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. D. Sheets, D. Holowka, and B. Baird Critical Role for Cholesterol in Lyn-mediated Tyrosine Phosphorylation of Fc{varepsilon}RI and Their Association with Detergent-resistant Membranes J. Cell Biol., May 17, 1999; 145(4): 877 - 887. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Galbiati, D. Volonte, D. Meani, G. Milligan, D. M. Lublin, M. P. Lisanti, and M. Parenti The Dually Acylated NH2-terminal Domain of Gi1alpha Is Sufficient to Target a Green Fluorescent Protein Reporter to Caveolin-enriched Plasma Membrane Domains. PALMITOYLATION OF CAVEOLIN-1 IS REQUIRED FOR THE RECOGNITION OF DUALLY ACYLATED G-PROTEIN alpha SUBUNITS IN VIVO J. Biol. Chem., February 26, 1999; 274(9): 5843 - 5850. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Ferguson The structure, biosynthesis and functions of glycosylphosphatidylinositol anchors, and the contributions of trypanosome research J. Cell Sci., January 9, 1999; 112(17): 2799 - 2809. [Abstract] [PDF]
|
|
|
|
|
|
F. Lafont, S. Lecat, P. Verkade, and K. Simons Annexin XIIIb Associates with Lipid Microdomains to Function in Apical Delivery J. Cell Biol., September 21, 1998; 142(6): 1413 - 1427. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Harder, P. Scheiffele, P. Verkade, and K. Simons Lipid Domain Structure of the Plasma Membrane Revealed by Patching of Membrane Components J. Cell Biol., May 18, 1998; 141(4): 929 - 942. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
W. G. Hill and M. L. Zeidel Reconstituting the Barrier Properties of a Water-tight Epithelial Membrane by Design of Leaflet-specific Liposomes J. Biol. Chem., September 22, 2000; 275(39): 30176 - 30185. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. W. Reagan Jr., M. L. Hubbert, and G. S. Shelness Posttranslational Regulation of Acid Sphingomyelinase in Niemann-Pick Type C1 Fibroblasts and Free Cholesterol-enriched Chinese Hamster Ovary Cells J. Biol. Chem., November 22, 2000; 275(48): 38104 - 38110. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Kakio, S.-i. Nishimoto, K. Yanagisawa, Y. Kozutsumi, and K. Matsuzaki Cholesterol-dependent Formation of GM1 Ganglioside-bound Amyloid beta -Protein, an Endogenous Seed for Alzheimer Amyloid J. Biol. Chem., June 29, 2001; 276(27): 24985 - 24990. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
A. Radhakrishnan, T. G. Anderson, and H. M. McConnell Condensed complexes, rafts, and the chemical activity of cholesterol in membranes PNAS, November 7, 2000; 97(23): 12422 - 12427. [Abstract] [Full Text] [PDF]
|
|
