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Journal of Cell Science, Vol 112, Issue 17 2799-2809, Copyright © 1999 by Company of Biologists
JOURNAL ARTICLES |
MA Ferguson
Division of Molecular Parasitology and Biological Chemistry, Department of Biochemistry, The Wellcome Trust Building, University of Dundee, Dundee DD1 5EH, UK. majferguson@bad.dundee.ac.uk
The discovery of glycosylphosphatidylinositol (GPI) membrane anchors has had a significant impact on several areas of eukaryote cell biology. Studies of the African trypanosome, which expresses a dense surface coat of GPI-anchored variant surface glycoprotein, have played important roles in establishing the general structure of GPI membrane anchors and in delineating the pathway of GPI biosynthesis. The major cell-surface molecules of related parasites are also rich in GPI-anchored glycoproteins and/or GPI-related glycophospholipids, and differences in substrate specificity between enzymes of trypanosomal and mammalian GPI biosynthesis may have potential for the development of anti-parasite therapies. Apart from providing stable membrane anchorage, GPI anchors have been implicated in the sequestration of GPI-anchored proteins into specialised membrane microdomains, known as lipid rafts, and in signal transduction events.
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|
|
|
|
|
|
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|
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|
|
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|
|
|
|
|
|
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|
|
|
|
|
|
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|
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|
 |
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|
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|
|
 |
|
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|
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|
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|
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|
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 |
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|
|
|
|
|
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|
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|
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|
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|
|
 |
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|
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|
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|
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I. White, A Souabni, and N. Hooper Comparison of the glycosyl-phosphatidylinositol cleavage/attachment site between mammalian cells and parasitic protozoa J. Cell Sci., January 2, 2000; 113(4): 721 - 727. [Abstract] [PDF]
|
|
|
|
|
|
T. D. Spurway, J. A. Dalley, S. High, and N. J. Bulleid Early Events in Glycosylphosphatidylinositol Anchor Addition. SUBSTRATE PROTEINS ASSOCIATE WITH THE TRANSAMIDASE SUBUNIT Gpi8p J. Biol. Chem., May 4, 2001; 276(19): 15975 - 15982. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Coussen, A. Ayon, A. Le Goff, J. Leroy, J. Massoulie, and S. Bon Addition of a Glycophosphatidylinositol to Acetylcholinesterase. PROCESSING, DEGRADATION, AND SECRETION J. Biol. Chem., July 20, 2001; 276(30): 27881 - 27892. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Abrami, M. Fivaz, T. Kobayashi, T. Kinoshita, R. G. Parton, and F. G. van der Goot Cross-talk between Caveolae and Glycosylphosphatidylinositol-rich Domains J. Biol. Chem., August 10, 2001; 276(33): 30729 - 30736. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
K. Nagamune, T. Nozaki, Y. Maeda, K. Ohishi, T. Fukuma, T. Hara, R. T. Schwarz, C. Sutterlin, R. Brun, H. Riezman, et al. Critical roles of glycosylphosphatidylinositol for Trypanosoma brucei PNAS, September 12, 2000; 97(19): 10336 - 10341. [Abstract] [Full Text] [PDF]
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