spacer gif spacer gif spacer gif spacer gif Propose a workshop for 2011 spacer gif
 QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    


This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Prydz, K.
Right arrow Articles by Dalen, K. T.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Prydz, K.
Right arrow Articles by Dalen, K. T.
Social Bookmarking
 Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Journal of Cell Science, Vol 113, Issue 2 193-205, Copyright © 2000 by Company of Biologists


JOURNAL ARTICLES

Synthesis and sorting of proteoglycans

K Prydz and KT Dalen
Department of Biochemistry and Institute for Nutrition Research, University of Oslo, Norway. kristian.prydz@biokjemi.uio.no.

Proteoglycans are widely expressed in animal cells. Interactions between negatively charged glycosaminoglycan chains and molecules such as growth factors are essential for differentiation of cells during development and maintenance of tissue organisation. We propose that glycosaminoglycan chains play a role in targeting of proteoglycans to their proper cellular or extracellular location. The variability seen in glycosaminoglycan chain structure from cell type to cell type, which is acquired by use of particular Ser-Gly sites in the protein core, might therefore be important for post-synthesis sorting. This links regulation of glycosaminoglycan synthesis to the post-Golgi fate of proteoglycans.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
Cancer Res.Home page
Q. Wei, R. Galbenus, A. Raza, R. L. Cerny, and M. A. Simpson
Androgen-Stimulated UDP-Glucose Dehydrogenase Expression Limits Prostate Androgen Availability without Impacting Hyaluronan Levels
Cancer Res., March 15, 2009; 69(6): 2332 - 2339.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. R. Garud, V. M. Tran, X. V. Victor, M. Koketsu, and B. Kuberan
Inhibition of Heparan Sulfate and Chondroitin Sulfate Proteoglycan Biosynthesis
J. Biol. Chem., October 24, 2008; 283(43): 28881 - 28887.
[Abstract] [Full Text] [PDF]


Home page
IOVSHome page
K. E. Keller, J. M. Bradley, M. J. Kelley, and T. S. Acott
Effects of Modifiers of Glycosaminoglycan Biosynthesis on Outflow Facility in Perfusion Culture
Invest. Ophthalmol. Vis. Sci., June 1, 2008; 49(6): 2495 - 2505.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Izumikawa, T. Koike, S. Shiozawa, K. Sugahara, J.-i. Tamura, and H. Kitagawa
Identification of Chondroitin Sulfate Glucuronyltransferase as Chondroitin Synthase-3 Involved in Chondroitin Polymerization: CHONDROITIN POLYMERIZATION IS ACHIEVED BY MULTIPLE ENZYME COMPLEXES CONSISTING OF CHONDROITIN SYNTHASE FAMILY MEMBERS
J. Biol. Chem., April 25, 2008; 283(17): 11396 - 11406.
[Abstract] [Full Text] [PDF]


Home page
J EndocrinolHome page
G. Levallet, J. Levallet, and P.-J. Bonnamy
FSH-induced phosphoprotein phosphatase 2A-mediated deactivation of particulate phosphodiesterase-4 activities is abolished after alteration in proteoglycan synthesis in immature rat Sertoli cells
J. Endocrinol., April 1, 2008; 197(1): 45 - 54.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
D. S. Woulfe, J. K. Lilliendahl, S. August, L. Rauova, M. A. Kowalska, M. Abrink, G. Pejler, J. G. White, and B. P. Schick
Serglycin proteoglycan deletion induces defects in platelet aggregation and thrombus formation in mice
Blood, April 1, 2008; 111(7): 3458 - 3467.
[Abstract] [Full Text] [PDF]


Home page
Nephrol Dial TransplantHome page
T. J. M. Wijnhoven, J. F. M. Lensen, R. G. Wismans, T. G. Hafmans, A. L. W. M. M. Rops, J. van der Vlag, J. H. M. Berden, L. P. W. J. van den Heuvel, and T. H. van Kuppevelt
In vivo blockade of sulphated domains of heparan sulphate in the glomerulus does not result in proteinuria
Nephrol. Dial. Transplant., February 14, 2008; (2008) gfm690v1.
[Abstract] [Full Text] [PDF]


Home page
GlycobiologyHome page
G. Dick, F. Grondahl, and K. Prydz
Overexpression of the 3'-Phosphoadenosine 5'-Phosphosulfate (PAPS) Transporter 1 Increases Sulfation of Chondroitin Sulfate in the Apical Pathway of MDCK II Cells
Glycobiology, January 1, 2008; 18(1): 53 - 65.
[Abstract] [Full Text] [PDF]


Home page
Am. J. Pathol.Home page
J. W.A.M. Celie, N. W.P. Rutjes, E. D. Keuning, R. Soininen, R. Heljasvaara, T. Pihlajaniemi, A. M. Drager, S. Zweegman, F. L. Kessler, R. H.J. Beelen, et al.
Subendothelial Heparan Sulfate Proteoglycans Become Major L-Selectin and Monocyte Chemoattractant Protein-1 Ligands upon Renal Ischemia/Reperfusion
Am. J. Pathol., June 1, 2007; 170(6): 1865 - 1878.
[Abstract] [Full Text] [PDF]


Home page
GlycobiologyHome page
H. Nakagawa, Y. Hama, T. Sumi, S.-C. Li, K. Maskos, K. Kalayanamitra, S. Mizumoto, K. Sugahara, and Y.-T. Li
Occurrence of a nonsulfated chondroitin proteoglycan in the dried saliva of Collocalia swiftlets (edible bird's-nest)
Glycobiology, February 1, 2007; 17(2): 157 - 164.
[Abstract] [Full Text] [PDF]


Home page
Plant CellHome page
M. J. Pena, R. Zhong, G.-K. Zhou, E. A. Richardson, M. A. O'Neill, A. G. Darvill, W. S. York, and Z.-H. Ye
Arabidopsis irregular xylem8 and irregular xylem9: Implications for the Complexity of Glucuronoxylan Biosynthesis
PLANT CELL, February 1, 2007; 19(2): 549 - 563.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Uyama, M. Ishida, T. Izumikawa, E. Trybala, F. Tufaro, T. Bergstrom, K. Sugahara, and H. Kitagawa
Chondroitin 4-O-Sulfotransferase-1 Regulates E Disaccharide Expression of Chondroitin Sulfate Required for Herpes Simplex Virus Infectivity
J. Biol. Chem., December 15, 2006; 281(50): 38668 - 38674.
[Abstract] [Full Text] [PDF]


Home page
FASEB J.Home page
L. Barre, N. Venkatesan, J. Magdalou, P. Netter, S. Fournel-Gigleux, and M. Ouzzine
Evidence of calcium-dependent pathway in the regulation of human {beta}1,3-glucuronosyltransferase-1 (GlcAT-I) gene expression: a key enzyme in proteoglycan synthesis
FASEB J, August 1, 2006; 20(10): 1692 - 1694.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Schon, C. Prante, C. Bahr, J. Kuhn, K. Kleesiek, and C. Gotting
Cloning and Recombinant Expression of Active Full-length Xylosyltransferase I (XT-I) and Characterization of Subcellular Localization of XT-I and XT-II
J. Biol. Chem., May 19, 2006; 281(20): 14224 - 14231.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
G. Misinzo, P. L. Delputte, P. Meerts, D. J. Lefebvre, and H. J. Nauwynck
Porcine circovirus 2 uses heparan sulfate and chondroitin sulfate B glycosaminoglycans as receptors for its attachment to host cells.
J. Virol., April 1, 2006; 80(7): 3487 - 3494.
[Abstract] [Full Text] [PDF]


Home page
GlycobiologyHome page
M. Fuller, A. Chau, R. C. Nowak, J. J. Hopwood, and P. J. Meikle
A defect in exodegradative pathways provides insight into endodegradation of heparan and dermatan sulfates
Glycobiology, April 1, 2006; 16(4): 318 - 325.
[Abstract] [Full Text] [PDF]


Home page
GlycobiologyHome page
T. T. Vuong, K. Prydz, and H. Tveit
Differences in the apical and basolateral pathways for glycosaminoglycan biosynthesis in Madin-Darby canine kidney cells
Glycobiology, April 1, 2006; 16(4): 326 - 332.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
C. Qin, B. Huang, J. N. Wygant, B. W. McIntyre, C. H. McDonald, R. G. Cook, and W. T. Butler
A Chondroitin Sulfate Chain Attached to the Bone Dentin Matrix Protein 1 NH2-Terminal Fragment
J. Biol. Chem., March 24, 2006; 281(12): 8034 - 8040.
[Abstract] [Full Text] [PDF]


Home page
J. Cell Sci.Home page
J. Liu, C.-H. Chau, H. Liu, B. R. Jang, X. Li, Y.-S. Chan, and D. K. Y. Shum
Upregulation of chondroitin 6-sulphotransferase-1 facilitates Schwann cell migration during axonal growth.
J. Cell Sci., March 1, 2006; 119(Pt 5): 933 - 942.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
H. Tveit, G. Dick, V. Skibeli, and K. Prydz
A Proteoglycan Undergoes Different Modifications en Route to the Apical and Basolateral Surfaces of Madin-Darby Canine Kidney Cells
J. Biol. Chem., August 19, 2005; 280(33): 29596 - 29603.
[Abstract] [Full Text] [PDF]


Home page
Biol. Reprod.Home page
K. Ndiaye, T. Fayad, D. W. Silversides, J. Sirois, and J. G. Lussier
Identification of Downregulated Messenger RNAs in Bovine Granulosa Cells of Dominant Follicles Following Stimulation with Human Chorionic Gonadotropin
Biol Reprod, August 1, 2005; 73(2): 324 - 333.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. Flores-Diaz, A. Alape-Giron, G. Clark, B. Catimel, Y. Hirabayashi, E. Nice, J.-M. Gutierrez, R. Titball, and M. Thelestam
A Cellular Deficiency of Gangliosides Causes Hypersensitivity to Clostridium perfringens Phospholipase C
J. Biol. Chem., July 22, 2005; 280(29): 26680 - 26689.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. W. A. M. Celie, E. D. Keuning, R. H. J. Beelen, A. M. Drager, S. Zweegman, F. L. Kessler, R. Soininen, and J. van den Born
Identification of L-selectin Binding Heparan Sulfates Attached to Collagen Type XVIII
J. Biol. Chem., July 22, 2005; 280(29): 26965 - 26973.
[Abstract] [Full Text] [PDF]


Home page
Mol. Cell. Biol.Home page
T. B. Feyerabend, H. Hausser, A. Tietz, C. Blum, L. Hellman, A. H. Straus, H. K. Takahashi, E. S. Morgan, A. M. Dvorak, H. J. Fehling, et al.
Loss of Histochemical Identity in Mast Cells Lacking Carboxypeptidase A
Mol. Cell. Biol., July 15, 2005; 25(14): 6199 - 6210.
[Abstract] [Full Text] [PDF]


Home page
J BiochemHome page
E. M. Kozma, K. Olczyk, G. Wisowski, A. Glowacki, and R. Bobinski
Alterations in the Extracellular Matrix Proteoglycan Profile in Dupuytren's Contracture Affect the Palmar Fascia
J. Biochem., April 1, 2005; 137(4): 463 - 476.
[Abstract] [Full Text] [PDF]


Home page
J. Leukoc. Biol.Home page
M. J. Kwakkenbos, W. Pouwels, M. Matmati, M. Stacey, H.-H. Lin, S. Gordon, R. A. W. van Lier, and J. Hamann
Expression of the largest CD97 and EMR2 isoforms on leukocytes facilitates a specific interaction with chondroitin sulfate on B cells
J. Leukoc. Biol., January 1, 2005; 77(1): 112 - 119.
[Abstract] [Full Text] [PDF]


Home page
Proc. Natl. Acad. Sci. USAHome page
N. Venkatesan, L. Barre, A. Benani, P. Netter, J. Magdalou, S. Fournel-Gigleux, and M. Ouzzine
Stimulation of proteoglycan synthesis by glucuronosyltransferase-I gene delivery: A strategy to promote cartilage repair
PNAS, December 28, 2004; 101(52): 18087 - 18092.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Aono, Y. Tokita, T. Shuo, S. Yamauchi, F. Matsui, K. Nakanishi, K. Hirano, M. Sano, and A. Oohira
Glycosylation Site for Chondroitin Sulfate on the Neural Part-time Proteoglycan, Neuroglycan C
J. Biol. Chem., November 5, 2004; 279(45): 46536 - 46541.
[Abstract] [Full Text] [PDF]


Home page
Vet PatholHome page
K. Yabe, H. Satoh, Y. Ishii, T. Jindo, T. Sugawara, K. Furuhama, M. Goryo, and K. Okada
Early Pathophysiologic Feature of Arthropathy in Juvenile Dogs Induced by Ofloxacin, a Quinolone Antimicrobial Agent
Vet. Pathol., November 1, 2004; 41(6): 673 - 681.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Suda, S. Kamiyama, M. Suzuki, N. Kikuchi, K.-i. Nakayama, H. Narimatsu, Y. Jigami, T. Aoki, and S. Nishihara
Molecular Cloning and Characterization of a Human Multisubstrate Specific Nucleotide-sugar Transporter Homologous to Drosophila fringe connection
J. Biol. Chem., June 18, 2004; 279(25): 26469 - 26474.
[Abstract] [Full Text] [PDF]


Home page
GlycobiologyHome page
M. Fuller, P. J. Meikle, and J. J. Hopwood
Glycosaminoglycan degradation fragments in mucopolysaccharidosis I
Glycobiology, May 1, 2004; 14(5): 443 - 450.
[Abstract] [Full Text] [PDF]


Home page
BloodHome page
M. Stacey, G.-W. Chang, J. Q. Davies, M. J. Kwakkenbos, R. D. Sanderson, J. Hamann, S. Gordon, and H.-H. Lin
The epidermal growth factor-like domains of the human EMR2 receptor mediate cell attachment through chondroitin sulfate glycosaminoglycans
Blood, October 15, 2003; 102(8): 2916 - 2924.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
S. Gulberti, S. Fournel-Gigleux, G. Mulliert, A. Aubry, P. Netter, J. Magdalou, and M. Ouzzine
The Functional Glycosyltransferase Signature Sequence of the Human {beta}1,3-Glucuronosyltransferase Is a XDD Motif
J. Biol. Chem., August 22, 2003; 278(34): 32219 - 32226.
[Abstract] [Full Text] [PDF]


Home page
JCBHome page
X. Ai, A.-T. Do, O. Lozynska, M. Kusche-Gullberg, U. Lindahl, and C. P. Emerson Jr.
QSulf1 remodels the 6-O sulfation states of cell surface heparan sulfate proteoglycans to promote Wnt signaling
J. Cell Biol., July 21, 2003; 162(2): 341 - 351.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. Jonsson, E. Eklund, L.-A. Fransson, and A. Oldberg
Initiation of the Decorin Glycosaminoglycan Chain in the Endoplasmic Reticulum-Golgi Intermediate Compartment
J. Biol. Chem., June 6, 2003; 278(24): 21415 - 21420.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
D. G. Seidler, E. Breuer, K. J. Grande-Allen, V. C. Hascall, and H. Kresse
Core Protein Dependence of Epimerization of Glucuronosyl Residues in Galactosaminoglycans
J. Biol. Chem., October 25, 2002; 277(44): 42409 - 42416.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
K. Fjeldstad, M. E. Pedersen, T. T. Vuong, S. O. Kolset, L. M. Nordstrand, and K. Prydz
Sulfation in the Golgi Lumen of Madin-Darby Canine Kidney Cells Is Inhibited by Brefeldin A and Depends on a Factor Present in the Cytoplasm and on Golgi Membranes
J. Biol. Chem., September 20, 2002; 277(39): 36272 - 36279.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
T. Ninomiya, N. Sugiura, A. Tawada, K. Sugimoto, H. Watanabe, and K. Kimata
Molecular Cloning and Characterization of Chondroitin Polymerase from Escherichia coli Strain K4
J. Biol. Chem., June 7, 2002; 277(24): 21567 - 21575.
[Abstract] [Full Text] [PDF]


Home page
Clin. Cancer Res.Home page
M. A. Nash, M. T. Deavers, and R. S. Freedman
The Expression of Decorin in Human Ovarian Tumors
Clin. Cancer Res., June 1, 2002; 8(6): 1754 - 1760.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
J. L. Moriarity, K. J. Hurt, A. C. Resnick, P. B. Storm, W. Laroy, R. L. Schnaar, and S. H. Snyder
UDP-glucuronate Decarboxylase, a Key Enzyme in Proteoglycan Synthesis. CLONING, CHARACTERIZATION, AND LOCALIZATION
J. Biol. Chem., May 3, 2002; 277(19): 16968 - 16975.
[Abstract] [Full Text] [PDF]


Home page
J. Virol.Home page
P. L. Delputte, N. Vanderheijden, H. J. Nauwynck, and M. B. Pensaert
Involvement of the Matrix Protein in Attachment of Porcine Reproductive and Respiratory Syndrome Virus to a Heparinlike Receptor on Porcine Alveolar Macrophages
J. Virol., March 27, 2002; 76(9): 4312 - 4320.
[Abstract] [Full Text] [PDF]


Home page
DevelopmentHome page
A. Irie, E. A. Yates, J. E. Turnbull, and C. E. Holt
Specific heparan sulfate structures involved in retinal axon targeting
Development, January 1, 2002; 129(1): 61 - 70.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
R. L. Chen and A. D. Lander
Mechanisms Underlying Preferential Assembly of Heparan Sulfate on Glypican-1
J. Biol. Chem., March 2, 2001; 276(10): 7507 - 7517.
[Abstract] [Full Text] [PDF]


Home page
J. Biol. Chem.Home page
M. R. Evers, G. Xia, H.-G. Kang, M. Schachner, and J. U. Baenziger
Molecular Cloning and Characterization of a Dermatan-specific N-Acetylgalactosamine 4-O-Sulfotransferase
J. Biol. Chem., September 21, 2001; 276(39): 36344 - 36353.
[Abstract] [Full Text] [PDF]




© The Company of Biologists Ltd 2000