|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 114, Issue 10 1811-1820, Copyright © 2001 by Company of Biologists
JOURNAL ARTICLES |
ME Miller and FR Cross
The Rockefeller University, New York, NY 10021, USA. fcross@rockvax.rockefeller.edu
Cyclin-dependent kinase (CDK) activity is essential for eukaryotic cell cycle events. Multiple cyclins activate CDKs in all eukaryotes, but it is unclear whether multiple cyclins are really required for cell cycle progression. It has been argued that cyclins may predominantly act as simple enzymatic activators of CDKs; in opposition to this idea, it has been argued that cyclins might target the activated CDK to particular substrates or inhibitors. Such targeting might occur through a combination of factors, including temporal expression, protein associations, and subcellular localization.
This article has been cited by other articles:
|
|
 |
|
  L. A. Simmons Kovacs, C. L. Nelson, and S. B. Haase Intrinsic and Cyclin-dependent Kinase-dependent Control of Spindle Pole Body Duplication in Budding Yeast Mol. Biol. Cell, August 1, 2008; 19(8): 3243 - 3253. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Hu, Y. Gan, and O. M. Aparicio Identification of Clb2 Residues Required for Swe1 Regulation of Clb2-Cdc28 in Saccharomyces cerevisiae Genetics, June 1, 2008; 179(2): 863 - 874. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. R. Cross, L. Schroeder, and J. M. Bean Phosphorylation of the Sic1 Inhibitor of B-Type Cyclins in Saccharomyces cerevisiae Is Not Essential but Contributes to Cell Cycle Robustness Genetics, July 1, 2007; 176(3): 1541 - 1555. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. K. Fung, H. T. Ma, and R. Y.C. Poon Specialized Roles of the Two Mitotic Cyclins in Somatic Cells: Cyclin A as an Activator of M Phase-promoting Factor Mol. Biol. Cell, May 1, 2007; 18(5): 1861 - 1873. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. K. Hungerbuehler, P. Philippsen, and A. S. Gladfelter Limited Functional Redundancy and Oscillation of Cyclins in Multinucleated Ashbya gossypii Fungal Cells Eukaryot. Cell, March 1, 2007; 6(3): 473 - 486. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Bloom and F. R. Cross Novel Role for Cdc14 Sequestration: Cdc14 Dephosphorylates Factors That Promote DNA Replication Mol. Cell. Biol., February 1, 2007; 27(3): 842 - 853. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. A. Daniel, B. E. Keyes, Y. P. Y. Ng, C. O. Freeman, and D. J. Burke Diverse Functions of Spindle Assembly Checkpoint Genes in Saccharomyces cerevisiae Genetics, January 1, 2006; 172(1): 53 - 65. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Remus, M. Blanchette, D. C. Rio, and M. R. Botchan CDK Phosphorylation Inhibits the DNA-binding and ATP-hydrolysis Activities of the Drosophila Origin Recognition Complex J. Biol. Chem., December 2, 2005; 280(48): 39740 - 39751. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Queralt and J. C. Igual Functional Connection Between the Clb5 Cyclin, the Protein Kinase C Pathway and the Swi4 Transcription Factor in Saccharomyces cerevisiae Genetics, December 1, 2005; 171(4): 1485 - 1498. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. L. Persson, Q. Zhang, X. Y. Wang, S. E Ravnik, S. Muhlrad, and D. J Wolgemuth Distinct roles for the mammalian A-type cyclins during oogenesis Reproduction, October 1, 2005; 130(4): 411 - 422. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 F. Hu and O. M. Aparicio Swe1 regulation and transcriptional control restrict the activity of mitotic cyclins toward replication proteins in Saccharomyces cerevisiae PNAS, June 21, 2005; 102(25): 8910 - 8915. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Gildor, R. Shemer, A. Atir-Lande, and D. Kornitzer Coevolution of Cyclin Pcl5 and Its Substrate Gcn4 Eukaryot. Cell, February 1, 2005; 4(2): 310 - 318. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 C. Bouchoux, G. Hautbergue, S. Grenetier, C. Carles, M. Riva, and V. Goguel CTD kinase I is involved in RNA polymerase I transcription Nucleic Acids Res., November 1, 2004; 32(19): 5851 - 5860. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Queralt and J. C. Igual Functional Distinction Between Cln1p and Cln2p Cyclins in the Control of the Saccharomyces cerevisiae Mitotic Cycle Genetics, September 1, 2004; 168(1): 129 - 140. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. C. Hammarton, M. Engstler, and J. C. Mottram The Trypanosoma brucei Cyclin, CYC2, Is Required for Cell Cycle Progression through G1 Phase and for Maintenance of Procyclic Form Cell Morphology J. Biol. Chem., June 4, 2004; 279(23): 24757 - 24764. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. Wang, H. Kong, Y. Sun, X. Zhang, W. Zhang, N. Altman, C. W. dePamphilis, and H. Ma Genome-Wide Analysis of the Cyclin Family in Arabidopsis and Comparative Phylogenetic Analysis of Plant Cyclin-Like Proteins Plant Physiology, June 1, 2004; 135(2): 1084 - 1099. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 G. M. Wilmes, V. Archambault, R. J. Austin, M. D. Jacobson, S. P. Bell, and F. R. Cross Interaction of the S-phase cyclin Clb5 with an 'RXL' docking sequence in the initiator protein Orc6 provides an origin-localized replication control switch Genes & Dev., May 1, 2004; 18(9): 981 - 991. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Yang, N. Li, C. Wang, Y. Yu, L. Yuan, M. Zhang, and X. Cao Cyclin L2, a Novel RNA Polymerase II-associated Cyclin, Is Involved in Pre-mRNA Splicing and Induces Apoptosis of Human Hepatocellular Carcinoma Cells J. Biol. Chem., March 19, 2004; 279(12): 11639 - 11648. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Goda, T. Ishii, N. Nakajo, N. Sagata, and H. Kobayashi The RRASK Motif in Xenopus Cyclin B2 Is Required for the Substrate Recognition of Cdc25C by the Cyclin B-Cdc2 Complex J. Biol. Chem., May 23, 2003; 278(21): 19032 - 19037. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. D. Moore, J. A. Kirk, and T. Hunt Unmasking the S-Phase-Promoting Potential of Cyclin B1 Science, May 9, 2003; 300(5621): 987 - 990. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
T. Pramila, S. Miles, D. GuhaThakurta, D. Jemiolo, and L. L. Breeden Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle Genes & Dev., December 1, 2002; 16(23): 3034 - 3045. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Shemer, A. Meimoun, T. Holtzman, and D. Kornitzer Regulation of the Transcription Factor Gcn4 by Pho85 Cyclin Pcl5 Mol. Cell. Biol., August 1, 2002; 22(15): 5395 - 5404. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
D. Huang, J. Moffat, and B. Andrews Dissection of a Complex Phenotype by Functional Genomics Reveals Roles for the Yeast Cyclin-Dependent Protein Kinase Pho85 in Stress Adaptation and Cell Integrity Mol. Cell. Biol., July 15, 2002; 22(14): 5076 - 5088. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Aloy and R. B. Russell Interrogating protein interaction networks through structural biology PNAS, April 30, 2002; 99(9): 5896 - 5901. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Hoque, T. M. Young, C.-G. Lee, G. Serrero, M. B. Mathews, and T. Pe'ery The Growth Factor Granulin Interacts with Cyclin T1 and Modulates P-TEFb-Dependent Transcription Mol. Cell. Biol., March 1, 2002; 23(5): 1688 - 1702. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. R. Cross, V. Archambault, M. Miller, and M. Klovstad Testing a Mathematical Model of the Yeast Cell Cycle Mol. Biol. Cell, January 1, 2002; 13(1): 52 - 70. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
P. Aloy and R. B. Russell Interrogating protein interaction networks through structural biology PNAS, April 30, 2002; 99(9): 5896 - 5901. [Abstract] [Full Text] [PDF]
|
|
