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First published online June 28, 2004
doi: 10.1242/10.1242/jcs.01203
Research Article |
1 Institute of Botany, University of Vienna, Rennweg 14, A-1030 Vienna, Austria
2 NWCRF Cancer Research Unit, School of Biological Sciences, University of Wales Bangor, Deiniol Road, Bangor, Gwynedd, LL57 2UW, UK
3 Bioinformatics Group, Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria
* Author for correspondence (e-mail: josef.loidl{at}univie.ac.at)
Accepted 8 March 2004
The fission yeast Schizosaccharomyces pombe does not form synaptonemal complexes (SCs) in meiotic prophase nuclei. Instead, thin threads, the so-called linear elements (LEs), are observed at the corresponding stages by electron microscopy. Here, we demonstrate that S. pombe Rec10 is a protein related to the Saccharomyces cerevisiae SC protein Red1 and that it localizes to LEs. Moreover, a homologue to S. cerevisiae Hop1 does exist in S. pombe and we show by in situ immunostaining that it, and the kinase Mek1 (a homologue of which is also known to be associated with SCs), localizes to LEs. These observations indicate the evolutionary relationship of LEs with the lateral elements of SCs and suggest that these structures might exert similar functions in S. cerevisiae and S. pombe.
Key words: Chromosome pairing, Meiosis, Recombination, Yeast
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