|
|
|
|
|
||
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
First published online April 24, 2006
doi: 10.1242/10.1242/jcs.02963
Commentary |
Center for Basic Research in Digestive Diseases and Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, 200 First Street SW, Rochester, MN 55905, USA
* Author for correspondence (e-mail: mcniven.mark{at}mayo.edu)
Accepted 28 February 2006
The large GTPase dynamin, long known for its role in endocytosis, has most recently been implicated as a facilitator of cell migration and invasion. Recent observations link dynamin to the cycle of membrane expansion and retraction essential for cell motility. Its role in actin polymerization, membrane deformation and vesiculation, and focal adhesion dynamics are all important for this process, and the new findings provide exciting directions for studies of this ubiquitous and diverse protein family.
Key words: Dynamin, Cell Motility, Migration, Invasion
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati 
Twitter What's this?
This article has been cited by other articles:
|
|
 |
|
  H. Cao, J. Chen, E. W. Krueger, and M. A. McNiven Src-Mediated Phosphorylation of Dynamin and Cortactin Regulates the "Constitutive" Endocytosis of Transferrin Mol. Cell. Biol., February 1, 2010; 30(3): 781 - 792. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 A. L. Hawthorne, C. J. Wylie, L. T. Landmesser, E. S. Deneris, and J. Silver Serotonergic Neurons Migrate Radially through the Neuroepithelium by Dynamin-Mediated Somal Translocation J. Neurosci., January 13, 2010; 30(2): 420 - 430. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 J. Saarikangas, H. Zhao, and P. Lappalainen Regulation of the Actin Cytoskeleton-Plasma Membrane Interplay by Phosphoinositides Physiol Rev, January 1, 2010; 90(1): 259 - 289. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. A. Singleton, S. Pendyala, I. A. Gorshkova, N. Mambetsariev, J. Moitra, J. G. N. Garcia, and V. Natarajan Dynamin 2 and c-Abl Are Novel Regulators of Hyperoxia-mediated NADPH Oxidase Activation and Reactive Oxygen Species Production in Caveolin-enriched Microdomains of the Endothelium J. Biol. Chem., December 11, 2009; 284(50): 34964 - 34975. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 O. L. Mooren and D. A. Schafer Constricting membranes at the nano and micro scale PNAS, December 8, 2009; 106(49): 20559 - 20560. [Full Text] [PDF]
|
|
|
|
 |
|
 J. A. W. Heymann and J. E. Hinshaw Dynamins at a glance J. Cell Sci., October 1, 2009; 122(19): 3427 - 3431. [Full Text] [PDF]
|
|
|
|
 |
|
 T. Itoh, J. Hasegawa, K. Tsujita, Y. Kanaho, and T. Takenawa The Tyrosine Kinase Fer Is a Downstream Target of the PLD-PA Pathway that Regulates Cell Migration Sci. Signal., September 8, 2009; 2(87): ra52 - ra52. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
O. L. Mooren, T. I. Kotova, A. J. Moore, and D. A. Schafer Dynamin2 GTPase and Cortactin Remodel Actin Filaments J. Biol. Chem., September 4, 2009; 284(36): 23995 - 24005. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Poincloux, F. Lizarraga, and P. Chavrier Matrix invasion by tumour cells: a focus on MT1-MMP trafficking to invadopodia J. Cell Sci., September 1, 2009; 122(17): 3015 - 3024. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
F. Jaskolski, B. Mayo-Martin, D. Jane, and J. M. Henley Dynamin-dependent Membrane Drift Recruits AMPA Receptors to Dendritic Spines J. Biol. Chem., May 1, 2009; 284(18): 12491 - 12503. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
R. Lundmark and S. R. Carlsson SNX9 - a prelude to vesicle release J. Cell Sci., January 1, 2009; 122(1): 5 - 11. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y.-W. Liu, M. C. Surka, T. Schroeter, V. Lukiyanchuk, and S. L. Schmid Isoform and Splice-Variant Specific Functions of Dynamin-2 Revealed by Analysis of Conditional Knock-Out Cells Mol. Biol. Cell, December 1, 2008; 19(12): 5347 - 5359. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. Jiang, A. Enomoto, M. Jijiwa, T. Kato, T. Hasegawa, M. Ishida, T. Sato, N. Asai, Y. Murakumo, and M. Takahashi An Actin-Binding Protein Girdin Regulates the Motility of Breast Cancer Cells Cancer Res., March 1, 2008; 68(5): 1310 - 1318. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
I. Rapoport, W. Boll, A. Yu, T. Bocking, and T. Kirchhausen A Motif in the Clathrin Heavy Chain Required for the Hsc70/Auxilin Uncoating Reaction Mol. Biol. Cell, January 1, 2008; 19(1): 405 - 413. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Cao, J. Chen, M. Awoniyi, J. R. Henley, and M. A. McNiven Dynamin 2 mediates fluid-phase micropinocytosis in epithelial cells J. Cell Sci., December 1, 2007; 120(23): 4167 - 4177. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. C. Henry, X. Daniell, M. Indaram, J. F. Whitesides, G. D. Sempowski, D. Howell, T. Oliver, and G. A. Taylor Impaired Macrophage Function Underscores Susceptibility to Salmonella in Mice Lacking Irgm1 (LRG-47) J. Immunol., November 15, 2007; 179(10): 6963 - 6972. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
H. Yamada, E. Ohashi, T. Abe, N. Kusumi, S.-A. Li, Y. Yoshida, M. Watanabe, K. Tomizawa, Y. Kashiwakura, H. Kumon, et al. Amphiphysin 1 Is Important for Actin Polymerization during Phagocytosis Mol. Biol. Cell, November 1, 2007; 18(11): 4669 - 4680. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 P. P Y Lie, W. Xia, C. Q F Wang, D. D Mruk, H. H N Yan, C.-h. Wong, W. M Lee, and C Y. Cheng Dynamin II interacts with the cadherin- and occludin-based protein complexes at the blood-testis barrier in adult rat testes J. Endocrinol., December 1, 2006; 191(3): 571 - 586. [Abstract] [Full Text] [PDF]
|
|
