|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 12, 707-723, Copyright © 1973 by Company of Biologists
Submitted on August 11, 1972
1 MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, England
Filaments of Anabaena have a spaced pattern of differentiated cells called heterocysts, which is maintained as a filament grows by the regular determination of new heterocysts. By following the growth of every cell in a filament, we have identified proheterocysts (prospective heterocysts) at their earliest appearance, and described the sequence of events in the formation of the pattern. The determination of proheterocysts obeys 2 rules: (1) that there are inhibitory zones around pre-existing heterocysts, and (2) that only the smaller daughter of a division can become a heterocyst (all divisions are asymmetrical). There are, however, certain conditions in which these rules are over-ridden, where a pattern consisting of groups of consecutive proheterocysts is seen which resolves into a normal discrete pattern. This process is highly suggestive of interaction between developing cells. We have tested this hypothesis in normal growth conditions by breaking filaments near to early proheterocysts, on the assumption that this will cause a build-up of inhibitory effect of the cell upon itself. It is found that these cells regress, losing their differentiated character and dividing. We therefore propose an interactive model for pattern formation in Anabaena.
Submitted on August 11, 1972
This article has been cited by other articles:
|
|
 |
|
  L. Shi, J.-H. Li, Y. Cheng, L. Wang, W.-L. Chen, and C.-C. Zhang Two Genes Encoding Protein Kinases of the HstK Family Are Involved in Synthesis of the Minor Heterocyst-Specific Glycolipid in the Cyanobacterium Anabaena sp. Strain PCC 7120 J. Bacteriol., July 15, 2007; 189(14): 5075 - 5081. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. El-Shehawy, C. Lugomela, A. Ernst, and B. Bergman Diurnal expression of hetR and diazocyte development in the filamentous non-heterocystous cyanobacterium Trichodesmium erythraeum Microbiology, May 1, 2003; 149(5): 1139 - 1146. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
Y. Dong, X. Huang, X.-Y. Wu, and J. Zhao Identification of the Active Site of HetR Protease and Its Requirement for Heterocyst Differentiation in the Cyanobacterium Anabaena sp. Strain PCC 7120 J. Bacteriol., March 15, 2000; 182(6): 1575 - 1579. [Abstract] [Full Text]
|
|
|
|
 |
|
 J. Larkin, N Young, M Prigge, and M. Marks The control of trichome spacing and number in Arabidopsis Development, January 3, 1996; 122(3): 997 - 1005. [Abstract] [PDF]
|
|
|
|
|
|
S Roth and T Schupbach The relationship between ovarian and embryonic dorsoventral patterning in Drosophila Development, January 8, 1994; 120(8): 2245 - 2257. [Abstract] [PDF]
|
|
|
|
|
|
C. Cabrera The generation of cell diversity during early neurogenesis in Drosophila Development, January 8, 1992; 115(4): 893 - 901. [PDF]
|
|
|
|
 |
|
 W J Buikema and R Haselkorn Characterization of a gene controlling heterocyst differentiation in the cyanobacterium Anabaena 7120. Genes & Dev., February 1, 1991; 5(2): 321 - 330. [Abstract] [PDF]
|
|
|
|
 |
|
 N. Baker, M Mlodzik, and G. Rubin Spacing differentiation in the developing Drosophila eye: a fibrinogen-related lateral inhibitor encoded by scabrous Science, December 7, 1990; 250(4986): 1370 - 1377. [Abstract] [PDF]
|
|
|
|
|
|
G. Mitchison, M Wilcox, and R. Smith Measurement of an inhibitory zone Science, February 27, 1976; 191(4229): 866 - 868. [Abstract] [PDF]
|
|
