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Journal of Cell Science, Vol 15, 177-183, Copyright © 1974 by Company of Biologists

Submitted on September 25, 1973

The Analysis of Malignancy by Cell Fusion

V. Further Evidence of the Ability of Normal Diploid Cells to Suppress Malignancy

F. WIENER 1, G. KLEIN 1, and H. HARRIS 2

1 Department of Tumour Biology, Karolinska Institutet 104 01 Stockholm 60, Sweden
2 Sir William Dunn School of Pathology, University of Oxford Oxford OXI 3RE, England

When cells of a highly malignant fibroblastic cell line, A9HT, are fused with normal diploid lymphocytes, malignancy is suppressed; but it is not suppressed when A9HT cells are fused with cells of a malignant lymphoma.

Submitted on September 25, 1973




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© The Company of Biologists Ltd 1974