spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Wallace, H.
Right arrow Articles by Maden, M.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Wallace, H.
Right arrow Articles by Maden, M.

Journal of Cell Science, Vol 20, Issue 3 539-547, Copyright © 1976 by Company of Biologists

JOURNAL ARTICLES

The cell cycle during amphibian limb regeneration

H Wallace and M Maden

The duration of the cell cycle in the blastema of regenerating limbs of axolotls has been measured by means of [3H]thymidine pulse labelling and autoradiography. A chase was required to define the pulse period. An average cell cycle at 20 degrees C takes 53 h, S-phase takes 38 h; including parts of mitosis, G1 is 10 h and G2 is 5 h long. The protracted cycle and S-phase are consonant with the large genome in axolotis and other urodeles. The rapidly growing blastema probably contains a steady population of about 5000 proliferating cells, as there is a regular withdrawal of differentiating cells from the population. The kinds of determination which exist in this population of cells, or are exerted on it, are briefly considered.


This article has been cited by other articles:


Home page
 J. Cell Sci.Home page
M. Bettencourt-Dias, S. Mittnacht, and J. P. Brockes
Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes
J. Cell Sci., October 1, 2003; 116(19): 4001 - 4009.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Biol.Home page
E. M. Tanaka, A. A.F. Gann, P. B. Gates, and J. P. Brockes
Newt Myotubes Reenter the Cell Cycle by Phosphorylation of the Retinoblastoma Protein
J. Cell Biol., January 13, 1997; 136(1): 155 - 165.
[Abstract] [Full Text] [PDF]


© The Company of Biologists Ltd 1976