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Journal of Cell Science, Vol 21, Issue 2 341-359, Copyright © 1976 by Company of Biologists

JOURNAL ARTICLES

Ultrastructural site variations in mouse epidermal organization

TD Allen and CS Potten

Mouse dorsal, ear, tail and foot epidermis are compared according to their tissue architecture and cell kinetics. Cell proliferation is expected in terms of the daily volume of keratin replaced. The stratum corneum may be organized into vertical columns of squames, which may have minimal overlap as in dorsum and ear, or maximal overlap as in tail. Individual areas are adapted to their function both in squame fine structure and rate of cell replacement. The surface keratin loss/replacement rate is at its highest in foot and tail, and lowest in ear and dorsum. Observations on hairless mouse dorsum are also included.




© The Company of Biologists Ltd 1976