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Journal of Cell Science, Vol 4, 17-24, Copyright © 1969 by Company of Biologists

Submitted on February 2, 1968

Pseudopodium Induction by the Action of Quaternary Ammonium Ions on Amoeba Proteus

J. E. BREWER 1 and L. G. E. BELL 1

1 Department of Zoology, University of Southampton, Southampton, England

Some aliphatic long-chain quaternary ammonium compounds and choline derivatives have been examined for their ability to induce pseudopodia from Amoeba proteus. The reaction involved in pseudopodium induction is believed to be between the quaternary nitrogen cations and polysaccharides on the cell surface. Not all of the carboxyl groups of the polysaccharide are involved in this reaction. The mechanism of pseudopodium induction is discussed in terms of changes in the surface charge and the permeability of the cell membrane.

Submitted on February 2, 1968






© The Company of Biologists Ltd 1969