spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Frankel, J.
Right arrow Articles by Frankel, A. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Frankel, J.
Right arrow Articles by Frankel, A. K.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Journal of Cell Science, Vol 43, Issue 1 59-74, Copyright © 1980 by Company of Biologists

JOURNAL ARTICLES

Temperature-sensitive periods of mutations affecting cell division in Tetrahymena thermophila

J Frankel, J Mohler and AK Frankel

Temperature-sensitive periods were determined by application of temperature shifts and shocks to 3 temperature-sensitive cell division arrest (cda) mutants of Tetrahymena thermophila. A restrictive temperature, 36 degrees C, was found at which all 3 mutants are fully penetrant, yet other physiological effects are minimal. At this temperature, the temperature-sensitive period of cdaC2 is a unique 5-min period in mid-division, that of cdaA1 is a similarly brief period situated about 0.5 h prior to cell division, while the temperature-sensitive period of cdaH1 is 20 to 30 min long and immediately precedes cell division. These periods either coincide with (cdaC2, cdaH1) or immediately precede (cdaA1) the onset of phenotypic abnormality at the restrictive temperature. Brief exposure to 36 degrees C during the temperature-sensitive period in any of these mutants brings about irreversible arrest of division furrows in progress or preparation. Mutant cells suffering such arrest can, however, divide again at a permissive temperature by forming new furrows at different sites.
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?


This article has been cited by other articles:


Home page
 Eukaryot CellHome page
J. Frankel
What Do Genic Mutations Tell Us about the Structural Patterning of a Complex Single-Celled Organism?
Eukaryot. Cell, October 1, 2008; 7(10): 1617 - 1639.
[Full Text] [PDF]

Home page
 Eukaryot CellHome page
N. E. Williams, C.-C. Tsao, J. Bowen, G. L. Hehman, R. J. Williams, and J. Frankel
The Actin Gene ACT1 Is Required for Phagocytosis, Motility, and Cell Separation of Tetrahymena thermophila
Eukaryot. Cell, March 1, 2006; 5(3): 555 - 567.
[Abstract] [Full Text] [PDF]

Home page
 J. Cell Sci.Home page
K Gonda, M Katoh, K Hanyu, Y Watanabe, and O Numata
Ca(2+)/calmodulin and p85 cooperatively regulate an initiation of cytokinesis in Tetrahymena
J. Cell Sci., January 11, 1999; 112(21): 3619 - 3626.
[Abstract] [PDF]


© The Company of Biologists Ltd 1980