|
|
|
|
|
|
|
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 5, 509-529, Copyright © 1969 by Company of Biologists
Submitted on January 24, 1969
1 Department of Human Anatomy Oxford, England
The structural variations which occur in the dendritic spines of pyramidal neurons of the somatic sensory cortex of the cat are described, particular attention being paid to spines attached to different parts of the dendritic tree. Spines may be recognized particularly by the absence of neurotubules and the common presence of a spine apparatus, and they can be considered as pedunculated or sessile, depending upon the presence or absence of a narrow pedicle. Within these 2 categories spines may be rounded, cup-like or prismatic, can be large or small, and may show various degrees of inversion of the surface receiving a synaptic contact. While spines of every size and shape may be attached to dendrites of all diameters, there is a definite tendency for the largest spines to occur on the smallest dendrites and vice versa. Furthermore, the smallest dendrites possess the spines with the longest pedicles. Every dendritic spine receives 1 axon terminal containing spherical synaptic vesicles and ending in an asymmetrical synaptic contact. In addition, 10-20% of the spines receive a second terminal, which in some cases may contain spherical vesicles and terminate asymmetrically but in others contains small, flattened or pleomorphic vesicles and ends in a symmetrical contact. The additional terminal may end on the pedicle of the spine or on the parent dendrite near the attachment of the pedicle. In the latter site, asymmetrical synapses are commonly associated with an additional spine apparatus.
Submitted on January 24, 1969
This article has been cited by other articles:
|
|
 |
|
  J. M. Mateos, A. Luthi, N. Savic, B. Stierli, P. Streit, B. H. Gahwiler, and R. A. McKinney Synaptic modifications at the CA3 CA1 synapse after chronic AMPA receptor blockade in rat hippocampal slices J. Physiol., May 15, 2007; 581(1): 129 - 138. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 Y. Kubota, S. Hatada, S. Kondo, F. Karube, and Y. Kawaguchi Neocortical Inhibitory Terminals Innervate Dendritic Spines Targeted by Thalamocortical Afferents J. Neurosci., January 31, 2007; 27(5): 1139 - 1150. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 I Ballesteros-Yanez, E Ambrosio, R Benavides-Piccione, J Perez, I Torres, M Miguens, C Garcia-Lecumberri, and J DeFelipe The Effects of Morphine Self-Administration on Cortical Pyramidal Cell Structure in Addiction-Prone Lewis Rats Cereb Cortex, January 1, 2007; 17(1): 238 - 249. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Zhao, E. M. Teng, R. G. Summers Jr, G.-l. Ming, and F. H. Gage Distinct Morphological Stages of Dentate Granule Neuron Maturation in the Adult Mouse Hippocampus J. Neurosci., January 4, 2006; 26(1): 3 - 11. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. N. Elston, R. Benavides-Piccione, and J. DeFelipe A Study of Pyramidal Cell Structure in the Cingulate Cortex of the Macaque Monkey with Comparative Notes on Inferotemporal and Primary Visual Cortex Cereb Cortex, January 1, 2005; 15(1): 64 - 73. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
M. Dierssen, R. Benavides-Piccione, C. Martinez-Cue, X. Estivill, J. Florez, G.N. Elston, and J. DeFelipe Alterations of Neocortical Pyramidal Cell Phenotype in the Ts65Dn Mouse Model of Down Syndrome: Effects of Environmental Enrichment Cereb Cortex, July 1, 2003; 13(7): 758 - 764. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
C. Gonzalez-Islas and J. J. Hablitz Dopamine Enhances EPSCs in Layer II-III Pyramidal Neurons in Rat Prefrontal Cortex J. Neurosci., February 1, 2003; 23(3): 867 - 875. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. N. Elston and K. S. Rockland The Pyramidal Cell of the Sensorimotor Cortex of the Macaque Monkey: Phenotypic Variation Cereb Cortex, October 1, 2002; 12(10): 1071 - 1078. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 D. Contreras, A. Destexhe, and M. Steriade Intracellular and Computational Characterization of the Intracortical Inhibitory Control of Synchronized Thalamic Inputs In Vivo J Neurophysiol, July 1, 1997; 78(1): 335 - 350. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
J. Spacek and K. M. Harris Three-Dimensional Organization of Smooth Endoplasmic Reticulum in Hippocampal CA1 Dendrites and Dendritic Spines of the Immature and Mature Rat J. Neurosci., January 1, 1997; 17(1): 190 - 203. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. Bear, L. Cooper, and F. Ebner A physiological basis for a theory of synapse modification Science, July 3, 1987; 237(4810): 42 - 48. [Abstract] [PDF]
|
|
|
|
|
|
R. Coss and A Globus Spine stems on tectal interneurons in jewel fish are shortened by social stimulation Science, May 19, 1978; 200(4343): 787 - 790. [Abstract] [PDF]
|
|
|
|
|
|
G. N. Elston Pyramidal Cells of the Frontal Lobe: All the More Spinous to Think With J. Neurosci., September 15, 2000; 20(18): RC95 - RC95. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
G. N. Elston and M. G. P. Rosa Pyramidal Cells, Patches, and Cortical Columns: a Comparative Study of Infragranular Neurons in TEO, TE, and the Superior Temporal Polysensory Area of the Macaque Monkey J. Neurosci., December 15, 2000; 20(24): RC117 - RC117. [Abstract] [Full Text] [PDF]
|
|
