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Journal of Cell Science, Vol 88, Issue 3 335-342, Copyright © 1987 by Company of Biologists

JOURNAL ARTICLES

A glycoprotein rapidly labelled with [14C]glucose present in a murine melanoma cell line

ME Bramwell
Sir William Dunn School of Pathology, Oxford, England.

If a murine melanoma cell line PG19 is metabolically labelled with [14C]glucose for a short time, one particular membrane component incorporates more radioactivity than the rest. This is a glycoprotein of about Mr 100,000, which is not preferentially labelled in non-malignant variants of the melanoma or in suppressed hybrid cells formed between PG19 and mouse fibroblasts.




© The Company of Biologists Ltd 1987