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Journal of Cell Science, Vol 93, Issue 3 419-426, Copyright © 1989 by Company of Biologists
JOURNAL ARTICLES |
SM Troyanovsky, VI Guelstein, TA Tchipysheva, VA Krutovskikh and GA Bannikov
All-Union Cancer Research Center, USSR Academy of Medical Sciences, Moscow.
By immunomorphology, using keratin 17-specific monoclonal antibody, it has been shown that this keratin is expressed only in the basal cells of a group of complex epithelia: glandular epithelium with myoepithelial component, transitional and pseudostratified epithelia. Immunolocalization of keratin 17 provides evidence that the expression of this keratin strongly depends on the cell position within epithelial structures. The topographical character of the keratin expression suggests that these proteins may be implicated in the generation of spatial organization of epithelial tissues.
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