|
|
|
|
|
||
|
|||||
| Home Help Feedback Subscriptions Archive Search Table of Contents | |||||
Journal of Cell Science, Vol 95, Issue 3 353-360, Copyright © 1990 by Company of Biologists
JOURNAL ARTICLES |
KS Kabnick and DA Peattie
Department of Tropical Public Health, Boston, Massachusetts 02115.
The protozoan parasite Giardia lamblia has the unusual morphology of bearing two equal-sized nuclei. This organism probably represents the earliest diverging lineage of eukaryotes, suggesting that its biological tactics may be transitional. To begin to understand the role played by the two equal-sized nuclei in this organism, and perhaps the role this organism has played along the path to higher eukaryotes, we have analyzed the structure and function of these two nuclei. We show that the two nuclei are equivalent with respect to the amount of DNA harbored in each nucleus, the presence of ribosomal DNA sequences, and the transcriptional activity. We begin also to address the question of how these bilaterally symmetrical ancestors divide, by illustrating the mitotic plane of division.
This article has been cited by other articles:
|
|
 |
|
  M. K. Poxleitner, M. L. Carpenter, J. J. Mancuso, C.-J. R. Wang, S. C. Dawson, and W. Z. Cande Evidence for Karyogamy and Exchange of Genetic Material in the Binucleate Intestinal Parasite Giardia intestinalis Science, March 14, 2008; 319(5869): 1530 - 1533. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. C. Dawson, M. S. Sagolla, J. J. Mancuso, D. J. Woessner, S. A. House, L. Fritz-Laylin, and W. Z. Cande Kinesin-13 Regulates Flagellar, Interphase, and Mitotic Microtubule Dynamics in Giardia intestinalis Eukaryot. Cell, December 1, 2007; 6(12): 2354 - 2364. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
S. Teodorovic, J. M. Braverman, and H. G. Elmendorf Unusually Low Levels of Genetic Variation among Giardia lamblia Isolates Eukaryot. Cell, August 1, 2007; 6(8): 1421 - 1430. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 M. S. Sagolla, S. C. Dawson, J. J. Mancuso, and W. Z. Cande Three-dimensional analysis of mitosis and cytokinesis in the binucleate parasite Giardia intestinalis J. Cell Sci., December 1, 2006; 119(23): 4889 - 4900. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
E. Nohynkova, P. Tumova, and J. Kulda Cell Division of Giardia intestinalis: Flagellar Developmental Cycle Involves Transformation and Exchange of Flagella between Mastigonts of a Diplomonad Cell. Eukaryot. Cell, April 1, 2006; 5(4): 753 - 761. [Abstract] [Full Text] [PDF]
|
|
|
|
|
|
L. Z. Yu, C. W. Birky Jr., and R. D. Adam The Two Nuclei of Giardia Each Have Complete Copies of the Genome and Are Partitioned Equationally at Cytokinesis Eukaryot. Cell, April 1, 2002; 1(2): 191 - 199. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 S. Ghosh, M. Frisardi, R. Rogers, and J. Samuelson How Giardia Swim and Divide Infect. Immun., December 1, 2001; 69(12): 7866 - 7872. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 H. G. Elmendorf, S. M. Singer, and T. E. Nash The abundance of sterile transcripts in Giardia lamblia Nucleic Acids Res., November 15, 2001; 29(22): 4674 - 4683. [Abstract] [Full Text] [PDF]
|
|
|
|
 |
|
 R. D. Adam Biology of Giardia lamblia Clin. Microbiol. Rev., July 1, 2001; 14(3): 447 - 475. [Abstract] [Full Text] [PDF]
|
|
