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Quarterly Journal of Microscopical Science, Vol s3-93, 391-394, Copyright © 1952 by Company of Biologists

Histochemical Distribution of 5-Nucleotidase in Snake Tissues: Presence of 5-Nucleotidase and Absence of Alkaline Phosphomonoesterase in Venom Glands of the Rattlesnake

D. E. BRAGDON 1 and J.F. A. MCMANUS 1

1 Schools of Anatomy and Pathology, University of Virginia, Department of Medicine, Charlottesville, Virginia

1. Activity of the specific alkaline phosphatase, 5-nucleotidase, is intense in the epithelium and secretion of the rattlesnake venom gland. Non-specific alkaline phosphatase activity is lacking.

2. Thyroid epithelium, the smooth muscle of great vessels, and (inconstantly) smooth muscle of abdominal hollow viscera show greater 5-nucleotidase than nonspecific activity.

3. These findings confirm the specificity of 5-nucleotidase.


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© The Company of Biologists Ltd 1952