spacer gif spacer gif spacer gif spacer gif spacer gif
QUICK SEARCH:   [advanced]


spacer gif
     Home     Help     Feedback     Subscriptions     Archive     Search     Table of Contents    

First published online April 5, 2005
doi: 10.1242/10.1242/jcs.02332

Journal of Cell Science 118, 1559-1563 (2005)
Published by The Company of Biologists 2005
This Article
Right arrow Summary Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Khosrotehrani, K.
Right arrow Articles by Bianchi, D. W.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Khosrotehrani, K.
Right arrow Articles by Bianchi, D. W.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Multi-lineage potential of fetal cells in maternal tissue: a legacy in reverse

Kiarash Khosrotehrani1 and Diana W. Bianchi2,*

1 Department of Dermatology, Tenon Hospital and UPRES EA2396, Saint-Antoine School of Medicine, Pierre et Marie Curie (Paris VI) University, 75020 Paris, France
2 Division of Genetics, Tufts-New England Medical Center, 750 Washington St, Boston, MA 02111, USA



View larger version (81K):

[in a new window]
  		Fig. 1. Microchimeric fetal cells in female thyroid express cytokeratin. Photomicrographs show FISH studies using Cy3-labeled X (orange) and FITC-labeled Y (green) chromosome probes, and immunofluorescence staining with anti-cytokeratin antibody, Texas Red (red). Nuclei are counterstained with DAPI (blue). (A) Male microchimeric cell in maternal thyroid with one Y chromosome (small arrow) and one X chromosome; 1000x magnification. (B) Same cell stained with anti-cytokeratin antibody (large arrow, red), indicating an epithelial cell; 1000x magnification. (C) Interphase FISH study of female thyroid tissue showing a group of male microchimeric cells; 400x magnification. Arrow shows one X and one Y chromosome. This group of cells did not stain positively for cytokeratin; therefore, they are not epithelial cells. (D) Combined FISH and immunofluorescence staining of a group of male microchimeric cells with one X and one Y (small arrow) chromosome. Note that in this plane of focus not all of the X chromosomes can be seen. This group of cells expresses cytokeratin (large arrow); 400x magnification.

 

Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?



© The Company of Biologists Ltd 2005