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Fig. 1. Cytoplasmic CHMP1 colocalizes with endosomes. COS7 cells were double-labeled with antibodies to CHMP1 and the indicated trafficking markers, and visualized by indirect immunofluorescence. Labeled structures are early endosomes, TfR and EEA1; late endosomes, Rab7; lysosomes, LAMP-1; medial and trans-Golgi, mannosidase II (Man II); and trans-Golgi, {gamma}-adaptin ({gamma}-adap). Note that CHMP1 and TfR patterns are most highly related.





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