Fig. 8. Expression of FAP-1 in pancreatic adenocarcinoma tissue revealed by
immunohistochemistry using the C-20 antibody. Note the positive staining in
the cytoplasm of pancreatic duct tumor cells of a stroma-rich tumor (a).
Immunostaining is absent from an adjacent tissue section where the C-20
antibody had been preincubated with the respective blocking peptide (b), from
the stromal compartment of tumor tissue and from pancreatic duct epithelium of
a healthy individual (e). Two further tumor tissue specimens with positive
staining are illustrated (c,d) of which one displayed a particularly strong
immunoreactivity (c). Counterstained with hemalum. Magnification 135x
(a,b,d,e); 270x (c).
