Fig. 6. Activation of the AhR delays clonal expansion in 3T3-L1 cells. (A) 3T3-L1
cells were grown to confluence. The cells were treated with 10 nM TCDD in the
differentiation medium. Control cells were given the same amount (2 µl) of
DMSO. Cell numbers were determined by taking hemocytometer cell counts. Each
time point represents a triplicate determination, and each experiment was
performed twice with similar results. (B) Cell growth curve during the clonal
expansion period in the various clones. Data represent means of determinations
made on three independent clones. The analysis was reproduced twice with
similar results. Symbols are defined in the figure.
