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Fig. 6. Transient overexpression of {alpha}T-catenin in {alpha}-catenin-negative HCT-8/R1 colon carcinoma cells restores cadherin/catenin-mediated cell-cell adhesion. At 10 hours after transfection with pE/L-GFP-haTctn plasmid and simultaneous infection with {Delta}A36R vaccinia virus, opposing cells expressing GFP-{alpha}T-catenin show increased fluorescence at their common cell-cell contacts (A). This results in recruitment of ß-catenin and E-cadherin to the same intercellular contact sites (B).





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