Fig. 8. Blocking of the incorporation of rED-A into cellular FN network by inhibitor of actin-myosin contractility. (A) Fibroblasts were incubated for 5 days in TGFß, then 100 µg/ml of biotinylated rED-A was added for 3 hours. A high incorporation (yellow) of rED-A (red) into the ED-A FN network (green) is visible. (B) ML-7 added into the culture medium 1hour before and during incubation with rED-A blocks rED-A incorporation into ED-A FN. Bar, 10 µm.

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