Fig. 3. Prophase/metaphase nuclear morphology. (a) FESEM image of prophase nucleus where vesicles are found at defined regions on the nuclear surface (arrows), presumably the nuclear poles, which are about to disrupt. (b) TEM thin section of more advanced stage of polar disruption in late prophase, showing membranes accumulating on the surface of the NE (arrowheads). (c) Low magnification TEM image showing disruption of poles (arrows) and penetration of the spindle microtubules in metaphase. (d,e) Mitotic NEs showing accumulated spindle membranes near or around the NE (arrowheads).
