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Fig. 2. Activation of CFTR-mediated iodide efflux by MPB-91 in IB3-1 cells. Iodide efflux experiments were carried out following a 2 hour incubation in the loading solution at 37°C with 250 µM MPB-91 compound (closed symbols) or not (open symbols). (A) MPB-91 (250 µM) stimulated iodide efflux only in MPB-treated cells (n=8 for each). (B) Bar graphs presenting the iodide efflux in IB3-1 cells after MPB treatment (filled bars). ***P<0.001.





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