Fig. 9. Lack of effect of NMDA on synaptic transmission in low Na+ solution. When Na+ concentration of the bath solution was reduced from 150 mM to 30 mM, fEPSP amplitudes dropped markedly within 10 minutes, but completely recovered within 30 minutes after application of basal Na+ concentration (open circles). Bath application of 3 µM NMDA for 10 minutes did not cause depression of fEPSP amplitudes in low Na+ solution (closed circles). Data are expressed as a percentage of baseline fEPSP amplitude (at time -40); means±s.e.m. of four slices.
