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Fig. 5. R-rings consist of intranuclear ER. Merged images of double immunofluorescence of HA-NoppR-transfected COS cells stained for HA-NoppR (red) and the ER marker proteins (green), Sec61 (A), SRP receptor (B), TRAM (C), TRAP{alpha} (D), BiP (E) PDI (F), HMG-CoA reductase (G), cytochrome P450 (H) and the IP3 receptor (I). Note the overlap in yellow and orange identifying the R-rings (two are pointed out by arrows in each panel). Bar, 10 µm.





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