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Fig. 5. Localisation of hDlg at cell junctions in differentiated cells inhibits its proteasome degradation. HaCaT skin keratinocytes and HeLa cervical carcinoma cells were either treated or not with CBZ proteasome inhibitor as indicated. hDlg was detected by FITC immunofluorescence and laser confocal microscopy. Representative pictures from 0.8 µm Z-axial slices are shown; settings for scanning were identical.
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