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Fig. 1. Domain composition of LAP, Lamp 1, Limp II and their chimeras. The domains of Lamp 1 are represented by open bars, LAP domains by grey bars and Limp II domains by hatched bars. In a first set of chimeras, the lumenal and transmembrane domains of LAP were substituted with the respective domains from Lamp 1 or Limp II. In the second set of chimeras, the cytoplasmic tail of LAP was substituted for that of Lamp 1 or Limp II.





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