Fig. 1. Immunolocalization of Cdk5. (A) Control section incubated with Cdk5 antibody in the presence of blocking peptide. (B) Section incubated with Cdk5 antibody, showing positive staining in the epithelium (single arrow) and the bow region (double arrow), extending to the suture (arrowhead). (C) Higher magnification of the bow region, showing stronger staining along the basal side of the epithelial cells (single arrow) and along the membranes of fiber cells (double arrow). (D) Higher magnification of the anterior portion of the lens, showing the unstained capsule (single arrow) and strong staining in the epithelium (double arrow). (E) Higher magnification of the elongating fiber cells showing strong staining along the capsule (single arrows), where fiber cells attach. (F) Cdk5 staining is substantially decreased at the suture (arrowhead). Bar, 250 µm (A,B); 125 µm (C-F).

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