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Fig. 3. The effects of InsP3, caffeine and carbachol (CCh) on STOCs. Depolarisation from -69 mV to -10 mV (iv) elevated [Ca2+]i (iii) and activated STOCs (ii). InsP3 ({uparrow}), caffeine (Caff, 10 mM, v) and CCh (50 µM) each increased [Ca2+]i (iii) and reversibly inhibited STOCs (ii and expanded time scale i).





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