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Fig. 4. Capacity of ionomycin and TPA to rescue IGF-I-mediated survival in Null
cells. Null cells were placed in suspension culture as described in
Fig. 2. 10% FBS, IGF-I (100
ng/ml), or ionomycin (2 µM) and TPA (100 ng/ml) were added as indicated.
Caspase 3 activity was measured 20 hours later.
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