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Fig. 7. PV biogenesis in IFN-{gamma}-treated macrophages infected with either L. amazonensis stationary phase or metacyclic promastigotes. Macrophages were processed as described in the legend to Fig. 5 to determine the association of the transferrin receptor, rab7p, lamp-1 and cathepsin B with phagosomes as a function of time. Results obtained after phagocytosis of stationary phase and metacyclic promastigotes are represented by broken and solid lines, respectively.





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